eBook - ePub
The multitasking molecular chaperone Hsp60
Structure, function, and impact on health and disease
- 400 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
The multitasking molecular chaperone Hsp60
Structure, function, and impact on health and disease
About this book
The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease provides an overview of this key component of the Chaperone System (CS). The book covers various areas of medicine in which Hsp60 chaperonopathies have been identified. Various chapters discuss the Hsp60 structure, localization, functions, and participation in disease mechanisms both genetic and acquired, focusing on humans but also presenting data obtained from pro- and eukaryotic experimental models. The main goal is to provide information accessible to all healthcare professionals in a way that can be understood by nonspecialists and that would stimulate clinical and pathological detection of Hsp60 chaperonopathies.Molecular mechanisms are briefly described with the purpose of illuminating roads toward accurate diagnosis, treatment, and patient monitoring. Consequently, the possibility of developing/applying chaperonotherapy centered on Hsp60, as a therapeutic tool or target, is analyzed in many sections of this book, across a variety of medical specialties. Over the last several years, the importance of the CS as a physiological system has been brought to prominence and its roles in health and disease made clear. The molecular chaperones, including Hsp60, are the key components of the CS that are typically cytoprotective, but they can also be etiopathogenic factors, causing diseases named chaperonopathies.
- Discusses strategies for diagnosis, patient monitoring, and treatment of disorders in which Hsp60 plays a role and can be used as biomarker and therapeutic target or agent
- Explains the fundamental biophysics, genetics, physiology, and pathogenicity of Hsp60
- Explores the mechanisms involving Hsp60 abnormalities causing disease, including carcinogenesis, inflammation, autoimmunity, and neurodegenerative disorders
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Yes, you can access The multitasking molecular chaperone Hsp60 by Francesco Cappello,Everly Conway de Macario,Alberto JL Macario in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Molecular Biology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- The multitasking molecular chaperone Hsp60
- Chapter One The chaperone system and its diseases
- Chapter Two Physical and biochemical properties of the molecular chaperone Hsp60
- Chapter Three The spectrum of human Hsp60 genetic variants and associated chaperonopathies
- Chapter Four Hsp60 in inflammation and autoimmunity
- Chapter Five Hsp60 and carcinogenesis
- Chapter Six Hsp60 involvement in articular cartilage tissue homeostasis and pathogenesis
- Chapter Seven Hsp60 and skeletal muscle diseases
- Chapter Eight Hsp60 and cardiovascular diseases
- Chapter Nine Hsp60 in physiology and pathophysiology of the respiratory system
- Chapter Ten Hsp60 and diseases of the digestive system
- Chapter Eleven The chaperone system and the pathophysiology of the urogenital apparatus
- Chapter Twelve Hsp60 and nervous system development and diseases
- Chapter Thirteen Hsp60 and pathophysiology of the neuroendocrine system
- Chapter Fourteen Hsp60 and artificial intelligence
- Appendix I: Supplementary material for Chapter 3
- Appendix II: Late-breaking news
- Index