Bacterial Enzymes as Targets for Drug Discovery

Meeting the Challenges of Antibiotic Resistance

Punit Kaur, Priyanka Sharma

• Publisher: Academic Press
• Year: 2024
• eBook ISBN:
  9780443222214
• Topic: Medicine
• Subtopic: Pharmacology

Bacterial Enzymes as Targets for Drug Discovery: Meeting the Challenges of Antibiotic Resistance addresses the gap between medical microbiology, structural biology, and genomic science in the development of new antibacterial drug development. This book consolidates detailed profiling of bacterial target enzyme families for the drug discovery process and methodologies for use and validation of the potential drug targets. The contents cover the foundations of the antibiotic drug discovery process and focus on bacterial enzymes as drug targets, building across these disciplines to provide a comprehensive resource in bacterial structural biology and genomics. This is the ideal reference for antibiotic drug discovery researchers in the pharma industry and academia. Biochemists, microbiologists, and medicinal chemists will also benefit from this books' content. - Provides strategies and approaches to drug design aiming at overcoming antibiotic resistance. - Includes most common roadblocks in identifying novel drug targets and presents the strategies to overcome. - Provides potential methods to identify new drug targets by genome mining.

Table of contents

• Front Cover
• Bacterial Enzymes as Targets for Drug Discovery
• Bacterial Enzymes as Targets for Drug Discovery: Foundations and Frontiers in EnzymologyMeeting the Challenges of Antibiotic Resistance
• Copyright
• Contents
• Contributors
• Preface
• I - Primer of the antibiotic discovery process
• II - Bacterial enzymes as drug targets
• List of abbreviations
• Index
• Back Cover