eBook - PDF
Mitophagy in Health and Disease
Mechanisms, Health Implications, and Therapeutic Opportunities
- 350 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Mitophagy in Health and Disease
Mechanisms, Health Implications, and Therapeutic Opportunities
About this book
Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.
This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.
- Covers biologic machinery and mechanisms involved with mitophagy
- Explores changes in mitophagy across the human lifespan
- Points out directions in targeting mitophagy with therapeutic interventions
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Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.
Yes, you can access Mitophagy in Health and Disease by John J. Lemasters in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Cell Biology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- Mitophagy in Health and Disease
- Copyright Page
- Contents
- List of contributors
- About the editor
- Preface
- 1 PINK1-Parkin quality control mitophagy pathway in Parkinson’s disease
- 2 Ubiquitin-independent mitophagy: mechanisms and pathophysiological functions
- 3 Role of AMPK/ULK1 signaling in mitophagy
- 4 Mitochondrial proteases
- 5 The mitochondrial unfolded protein response in health and disease
- 6 Mitochondria-derived vesicles: from quality control to inflammation and extracellular vesicles
- 7 Molecular regulation of mitochondrial turnover by exercise: tissue adaptation through mitochondrial biogenesis and mitophagy
- 8 Role of mitophagy and mitochondria in aging and cellular senescence
- 9 Mitophagy in erythropoiesis
- 10 The dual role of mitophagy in cancer and its targeting for effective anticancer therapy
- 11 Mitophagy and neurodegenerative disease
- 12 The antiaging role of mitophagy
- 13 Compromised mitophagy in aging and neurodegenerative diseases
- 14 Mitophagy inducers as potential therapeutic agents
- 15 Mitochondrial quality control and the microphthalmia/transcription factor E (MiTF/TFE) family
- 16 Cardioprotection through mitophagy
- 17 Fasting, mitophagy, and aging
- 18 Aldehydes, mitophagy, and the pathogenesis of alcohol-associated and metabolic dysfunction-associated steatohepatitis
- 19 Mitochondrial dynamics and quality control in alcohol-associated liver disease and liver tumorigenesis
- 20 The Sodom and Gomorrah conundrum of yeast mitophagy
- 21 Sphingolipid metabolism in the regulation of mitophagy: implications in cancer therapy, immune cell function, and neurod...
- 22 Formation of mitophagosomes
- 23 Mitophagy in hepatic ischemia/reperfusion
- Index
- Back Cover