During an interval of 15 years, the Lucille P. Markey Charitable Trust spent over $500 million on four programs in the basic biomedical sciences that support the education and research of graduate students, postdoctoral fellows, junior faculty, and senior researchers. The Markey Trust asked the NRC to evaluate these programs with two questions in mind: Were these funds well spent? and What can others in the biomedical and philanthropic communities learn from the programs of the Markey Trust, both as an approach to funding biomedical research and as a model of philanthropy? One of five resulting reports, this volume examines the Research Program Grants, which awarded $323 million to support investigators with a major commitment to the life sciences and to assist in the establishment, reorganization, or expansion of significant biomedical research centers or programs. Using information from Markey archives, materials from grant recipients, and site visits to a sample of institutional grant recipients, the authoring committee describes the impact that Markey grants made on the centers and programs funded by these grants, along with the unique aspects of the Markey approach to funding that may be applicable to other funders of biomedical research programs.

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Table of contents
- COVER PAGE
- THE NATIONAL ACADEMIES
- COMMITTEE FOR THE EVALUATION OF THE LUCILLE P. MARKEY CHARITABLE TRUST PROGRAMS IN BIOMEDICAL SCIENCES
- BOARD ON HIGHER EDUCATION AND WORKFORCE
- Preface and Acknowledgments
- Contents
- Summary
- Introduction
- History of the Markey Trust
- Grant Programs
- Background of the Research Program Grants
- Assessing the Markey Research Program Grants
- Outcomes of the Research Program Grants
- References
- Appendix A Overview and Description Lucille P. Markey Charitable Trust Research Program Grants Awards
- Appendix B Site Visit Reports Lucille P. Markey Charitable Trust Large Research Program Grant Awards
- Appendix C Site Visit Reports, Telephone Interviews, and Letter Reports Lucille P. Markey Charitable Trust Small Research Program Grant Awards
- Appendix D Outcome Measures for Research Program Grant Awardees
- Appendix E Biographies of Members of the Lucille P. Markey Charitable Trust Programs in Biomedical Sciences Committee
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