Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic
eBook - ePub

Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic

Interim Report

,
  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic

Interim Report

,

About this book

The US Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS) program develops toxicologic assessments of environmental contaminants. IRIS assessments provide hazard identification and dose-response assessment information. The information is then used in conjunction with exposure information to characterize risks to public health and may be used in risk-based decisionmaking, in regulatory actions, and for other risk-management purposes. Since the middle 1990s, EPA has been in the process of updating the IRIS assessment of inorganic arsenic. In response to a congressional mandate for an independent review of the IRIS assessment of inorganic arsenic, EPA requested that the National Research Council convene a committee to conduct a two-phase study. Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic is the report of the first phase of that study. This report evaluates critical scientific issues in assessing cancer and noncancer effects of oral exposure to inorganic arsenic and offers recommendations on how the issues could be addressed in EPA's IRIS assessment.

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Information

Publisher
National Academies Press
Year
2013
eBook ISBN
9780309297097
Edition
0
Topic
Physical Sciences

Table of contents

  1. COVER PAGE
  2. TITLE PAGE
  3. COPYRIGHT PAGE
  4. TABLE OF CONTENTS
  5. SUMMARY
  6. 1 INTRODUCTION
  7. 2 EXPOSURE CONSIDERATIONS
  8. 3 IRIS ASSESSMENT DEVELOPMENT PLANS: EVIDENCE EVALUATION, SYSTEMATIC REVIEW, AND META-ANALYSIS
  9. 4 HAZARD IDENTIFICATION
  10. 5 SUSCEPTIBILITY FACTORS
  11. 6 MODE OF ACTION
  12. 7 DOSE–RESPONSE ANALYSIS
  13. REFERENCES
  14. APPENDIXES