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About this book
With contributions from the leading researchers in the field, this volume brings together the latest studies on insulin action and signal transduction to provide a state-of-the-art reference for graduate researchers and students in diabetes and endocrinology. Insulin Signaling is a comprehensive study of the regulation of molecular events by insuli
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Yes, you can access Insulin Signaling by George Grunberger,Yehiel Zick in PDF and/or ePUB format, as well as other popular books in Medicine & Medical Theory, Practice & Reference. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Half Title
- Series Page
- Title Page
- Copyright Page
- Dedication Page
- Table of Contents
- Foreword
- Preface to the Series
- Preface
- Contributors
- 1 Mutations in the Insulin Receptor Gene
- 2 Insulin Receptor Folding
- 3 IRS Protein Structure
- 4 The Molecular Basis of Insulin Action
- 5 Grb-10 in Peptide Hormone Action
- 6 Regulation of Protein Kinase B: Implications for Insulin Signaling
- 7 Insulin Mediated S6 Kinase Activation: Role in Translation, Cell Growth and144Â Insulin Production
- 8 Role of Serine/Threonine Protein Kinase, Raf-1, in Insulin Mediated Metabolic163Â Signaling
- 9 PKC as Downstream Effector of PI3 Kinase in Rat Adipocytes
- 10 PIKfyve and Acute Insulin Actions
- 11 Insulin Action in Vascular Endothelium
- 12 GLUT4 Traffic Report: Molecular Mechanisms of Insulin-Stimulated GLUT4Â Trafficking in Adipocytes
- 13 Insulin Receptor Trafficking
- 14 Ser/Thr Phosphorylation of Insulin Receptor Signaling Molecules and Insulin Resistance
- 15 Tyrosine Kinase Inhibitors
- 16 Abnormal p85/p110 Type PI-Kinase Activation in Zucker Fatty Rats and High-Fat Fed Rats
- 17 The Role of PKC for Insulin Receptor Signaling
- 18 Pharmacological Approaches to Insulin Resistance in the Zucker Diabetic Fatty Rat
- 19 Lessons from Targeted Gene Knockouts of the Insulin Receptor Domenico Accili
- 20 Animal Models of IRS-1/IRS-2 Knockouts
- 21 Metabolic Perturbations in Mice Engineered to have altered GLUT4 Content
- 22 Glucose Transporters and Cardiac Function: Insights from Heart Selective GLUT4 Knockout Mice
- 23 Insights from Mouse Models Deficient in Protein-Tyrosine Phosphatases that Regulate the Insulin Action Pathway
- Index