Mitochondrial Signaling in Health and Disease
eBook - ePub

Mitochondrial Signaling in Health and Disease

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Mitochondrial Signaling in Health and Disease

About this book

Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic

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Yes, you can access Mitochondrial Signaling in Health and Disease by Sten Orrenius,Lester Packer,Enrique Cadenas in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2012
eBook ISBN
9781040198681
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Cover Page
  2. Halftitle Page
  3. OXIDATIVE STRESS AND DISEASE
  4. Title Page
  5. Copyright Page
  6. Contents
  7. Preface
  8. Editors
  9. Contributors
  10. Section I: Mitochondria—Reactive Oxygen Species (ROS)—Cell Death
  11. 1 Healthy Free Radical Pessimism
  12. 2 Mitochondrial Involvement in the Execution of Cell Death
  13. 3 Role of Protein Kinase C in Mitochondrial Functions in Cardiac Ischemia-Reperfusion Injury
  14. 4 Mitocans, Mitochondria-Targeting Anticancer Drugs
  15. 5 Therapeutic Potential of Lipoamide and Enhanced Mitochondrial Biogenesis for Treatment of Insulin Resistance
  16. 6 Mitochondria-Targeted Antioxidants
  17. Section II: Mitochondria—Metabolism—Nitric Oxide
  18. 7 Lactate Shuttling and the Mitochondrial Lactate Oxidation Complex
  19. O Nitric Oxide in the Regulation of Mitochondrial Biogenesis
  20. Q Effect of Sildenafil on Heart Nitric Oxide Metabolism and Mitochondrial Function
  21. 10 Kinases and Mitochondrial Cycling The Last Encounter
  22. Section III: Acetylation—Deacetylation —Aging
  23. 11 Nuclear Chromatin Factors Defining Mitochondrial Bioenergetics Implications in Age-Associated Diseases
  24. 12 Mitochondrial Protein Acetylation and Sirtuin- Mediated Deacetylation
  25. 13 Mitochondrial Regulation by Protein Acetylation
  26. 14 Calorie Restriction, Mitochondria, and Longevity in Saccharomyces cerevisiae
  27. 15 Autophagy and Aging
  28. Section IV: Neurodegeneration
  29. 16 Mitochondrial Dynamics and Its Implications in Metabolic Dysregulation and Neurodegeneration
  30. 1 7 Mitochondrial Abnormalities and Oxidative Stress in Alzheimer’s Disease
  31. 18 Role of Mitochondria in Parkinson’s Disease and Huntington’s Disease
  32. 19 a -Ketoglutarate Dehydrogenase Complex in Neurodegeneration
  33. 20 R-a-Lipoic Acid as a Potent Agent of Mitochondrial Protection in Alzheimer’s Disease
  34. 21 Mitochondrial Antioxidants in Neuroprotection