Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Goutam Brahmachari

• Publisher: CRC Press
• Year: 2013
• eBook ISBN:
  9781040192504
• Topic: Physical Sciences
• Subtopic: Pharmacology

Natural products play crucial roles in modern drug development, and constitute a prolific source of novel lead compounds or pharmacophores for ongoing drug discovery programs. Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds presents cutting-edge research in the chemistry of bioactive natural products and demonstrates how natur

Table of contents

• Cover
• Half Title
• Title Page
• Copyright Page
• Dedication
• Table of Contents
• Forewords
• Preface
• Editor
• Contributors
• 1 Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds
• 2 Impact of Solid-Supported Cyclization-Elimination Strategies toward the Development of Natural Product Inspired Molecules in Drug Discovery Research1
• 3 Synthesis and Biological Studies of Novel ß-Lactams2
• 4 Applications of Isatin Chemistry in Organic Synthesis and Medicinal Chemistry
• 5 Role of Organic Carbamates in Anticancer Drug Design
• 6 Rational Design of New Molecules of Biological Significance from Phenolic Constituents of Some Tropical Plants as Renewable Materials
• 7 Synthesis and Biological Activity of Promising Azole Marine Products Largazole and Neopeltolide
• 8 Omega-3 (œ-3) Polyunsaturated Fatty Acids
• 9 Structure and Biological Activity of Natural Melanin Pigments
• 10 Recent Acquisitions on Naturally Occurring Oxyprenylated Secondary Plant Metabolites
• 11 Role of Curcumin in Ameliorating Neuroinflammation and Neurodegeneration Associated with Alzheimer’s Disease
• 12 Plant Metabolites Inhibitors of NO Production
• 13 X-Ray Structural Behavior of Some Significant Bioactive Steroids and Their Chemistry in the Crystal Packing and Related Matters
• 14 Three-Dimensional Structure of Xanthones
• 15 Gambogic Acid A Caged Prenylated Garcinia Xanthone Potent Anticancer Agent of Pharmaceutical Promise3
• 16 Neuroplasticity as a New Approach to the Pathophysiology of Depression and the Role of Modern Antidepression Drugs
• 17 Statins Fermentation Products for Cholesterol Control in Humans
• 18 Molecular Aspects of Fungal Bioactive Polyketides
• 19 Marine Microalgal Metabolites A Promising Source of Pharmaceuticals
• 20 Rosmarinic Acid Biological, Pharmacological, and In Vitro Plant Cell Culture Approximation
• 21 Enhancement of Natural Antioxidants in Plants by Biosynthetic Pathway Modulation
• 22 Plant as Biofactories of Pharmaceuticals and Nutraceuticals