
Drug Stereochemistry
Analytical Methods and Pharmacology, Third Edition
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Drug Stereochemistry
Analytical Methods and Pharmacology, Third Edition
About this book
In recent years, sensor research has undergone a quiet revolution that will have a significant impact on a broad range of applications in areas such as health care, the environment, energy, food safety, national security, and manufacturing. Sensors for Chemical and Biological Applications discusses in detail the potential of chemical and biological sensors and examines how they are meeting the challenges of chem-bio terrorism by monitoring through enhanced specificity, fast response times, and the ability to determine multiple hazardous substances.
Exploring the nanotechnology approach, and carrying this theme throughout the book, the chapters cover the sensing principles for, chemical, electrical, chromatographic, magnetic, biological, fluidic, optical, and ultrasonic and mass sensing systems. They address issues associated with cost, synthesis, and testing of new low cost materials with high sensitivity, selectivity, robustness, and speed for defined sensor applications. The book extensively discusses the detailed analysis of future impact of chemical and biological sensors in day-to-day life.
Successful development of improved chemical sensor and biosensor systems and manufacturing procedures will not only increase the breadth and depth of the sensor industry, but will spill over into the design and manufacture of other types of sensors and devices that use nanofabrication and microfabrication techniques. This reference not only supplies versatile, hands-on tools useful in a broad array of disciplines, but also lays the interdisciplinary groundwork required for the achievement of sentient processing.
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Information
Table of contents
- Cover
- Half Title
- Title
- Copyright Page
- About the Editors
- Contents
- Contributors
- 1: The early history of stereochemistry
- 2: Stereochemistry—basic terms and concepts
- 3: Molecular basis of chiral recognition
- 4: Separation and resolution of enantiomers and their dissociable diastereomers through direct crystallization
- Indirect methods for the chromatographic resolution of drug enantiomers
- HPLC chiral stationary phases for the stereochemical resolution of enantiomeric compounds: The current state of the art
- Preparative and production scale chromatography in enantiomer separations
- Enantioselective separations by electromigration techniques
- Alternative analytical techniques for determination or isolation of drug enantiomers
- Stereoselective transport of drugs
- Enantioselective binding of drugs to plasma proteins
- Clinical pharmacokinetics
- Regulatory perspective on the development of new stereoisomeric drugs
- Molecular analysis of agonist stereoisomers at P2-adrenoceptors
- Development of chiral drugs from a U.S. legal patentability perspective: Enantiomers and racemates
- The importance of chiral separations in single enantiomer patent cases
- Index