Medications for Older Persons

Recommendations, Harms, Evidence

Roger Thomas

• Publisher: Academic Press
• Year: 2025
• Topic: Biological Sciences
• eBook ISBN:
  9780443290268
• Subtopic: Biology
• Index: Biological Sciences

Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons' alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention. - Conveys the benefit and harm profiles of medications for older persons - Outlines which randomized controlled trials (RCTs) of medication effects have the lowest risk of bias and highest GRADE quality - Discusses which randomized, controlled trials (RCTs) have the longest and most complete follow up and accounts for the key risk factors and confounders

Table of contents

• Title of Book
• 1. STOPP criteria and Beers' criteria for potentially inappropriate medications (PIMs), and START criteria for potential prescribing omissions (PPOs)
• 2. “Potentially inappropriate medications” and “potential prescribing omissions” of patients ≥65 hospitalized in Calgary, Canada, 2013–21, most strongly associated with readmissions and mortality, and costs compared to New Zealand, the lowest-cost OECD country
• 3. How STOPP/START and American Geriatrics Society criteria medications are metabolized by the P450 enzyme system and medication metabolism varies by genome
• 4. Methods to identify adverse drug interactions and events
• 5. Alcohol–medication interactions in older people
• 6. Improving medication list accuracy across transitions of care: Impacts on PIMs, PPOs, and adverse events in older adults
• 7. Hypertensive medications for older persons
• 8. Pharmacologic management of diabetes in older adults
• 9. Medications for anti-coagulation in stroke prevention
• 10. Medications for anxiety
• 11. Medications for insomnia
• 12. Neuroleptic/antipsychotic medications
• 13. Prevention and treatment of delirium in older persons
• 14. Efficacy and harms of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids for musculoskeletal pain in older persons
• 15. Medications for osteoporosis
• 16. Prescribing to prevent falls
• Index