Handbook of Practical Pharmacology - I

Suman Kamlesh Rattan, Kedar Prasad Meena, Venu Anand Das Vaishnav

• Publisher: Bentham Science Publishers
• Year: 2025
• eBook ISBN:
  9798898812195
• Topic: Medicine
• Subtopic: Pharmacology

Handbook of Practical Pharmacology – I serves as a vital bridge between theoretical pharmacology and laboratory application, equipping learners with the experimental skills essential to understanding drug actions through hands-on animal studies. A comprehensive, curriculum-based guide designed for second-year B. Pharm. students,
fully aligned with the Pharmacy Council of India's 2014 regulations. The book introduces students to fundamental laboratory concepts, animal handling as per CCSEA guidelines, drug administration routes, and experimental models like Rotarod, Actophotometer, and rabbit eye studies. It explores pharmacodynamic responses to various classes of drugs, including hepatic enzyme inducers, skeletal muscle relaxants, anticonvulsants, and anxiolytics. Each chapter combines clarity, precision, and ethical awareness, ensuring reproducibility and adherence to professional standards. Serving both as a laboratory manual and a learning companion, this handbook enhances analytical thinking and experimental competence, helping students gain a deeper, practice-based understanding of pharmacology. Key Features · Aligns with the PCI 2014 syllabus for second-year B. Pharm. students. · Explains fundamental experimental pharmacology concepts and instrumentation. · Demonstrates animal handling and drug administration techniques per CCSEA guidelines. · Guides pharmacodynamic testing using established models like Rotarod, Actophotometer, and MES. · Promotes laboratory competence, ethical compliance, and analytical reasoning in pharmacology.

Table of contents

• Welcome
• Table of Contents
• Title
• BENTHAM SCIENCE PUBLISHERS LTD.
• FOREWORD
• PREFACE
• Introduction to Experimental Pharmacology
• Instruments Used in Experimental Pharmacology Laboratory
• Study of Common Laboratory Animals
• Maintenance of Laboratory Animals as per CCSEA Guidelines
• Commonly Used Laboratory Techniques
• Study of Different Routes of Drug Administration in Murines
• Effects of Hepatic Microsomal Enzyme Inducers on Phenobarbitone-Induced Sleep Duration in Mice
• Drugs Acting on Ciliary Motility of Frog Esophagus
• Impact of Several Drugs on the Rabbit Eye
• Impact of Skeletal Muscle Relaxants Assessed via Rotarod Apparatus
• Effect of Drugs on the Locomotor Activity of Mice using Actophotometer
• Anticonvulsant Effect of Drugs by MES & PTZ Method
• Drugs Used for Anti-Cationic Activity and Stereotype-Like Behavior in Murinea
• Study of Anxiolytic Activity of Drugs Using the Murine
• Study of Local Anaesthetics by Different Methods