Lead: Its Effects on Environment and Health

Astrid Sigel, Helmut Sigel, Roland K.O. Sigel, Astrid Sigel, Helmut Sigel, Roland K.O. Sigel, Astrid Sigel, Helmut Sigel, Roland K. O. Sigel

• Publisher: De Gruyter
• Year: 2017
• eBook ISBN: 9783110433012
• Edition: 1
• Topic: Ciencias físicas
• Subtopic: Bioquímica en medicina

Volume 17, entitled Lead: Its Effects on Environment and Health of the series Metal Ions in Life Sciences centers on the interrelations between biosystems and lead. The book provides an up-to-date review of the bioinorganic chemistry of this metal and its ions; it covers the biogeochemistry of lead, its use (not only as gasoline additive) and anthropogenic release into the environment, its cycling and speciation in the atmosphere, in waters, soils, and sediments, and also in mammalian organs. The analytical tools to determine and to quantify this toxic element in blood, saliva, urine, hair, etc. are described. The properties of lead(II) complexes formed with amino acids, peptides, proteins (including metallothioneins), nucleobases, nucleotides, nucleic acids, and other ligands of biological relevance are summarized for the solid state and for aqueous solutions as well. All this is important for obtaining a coherent picture on the properties of lead, its effects on plants and toxic actions on mammalian organs. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 17, which are written by 36 internationally recognized experts from 13 nations. The impact of this recently again vibrant research area is manifested in nearly 2000 references, over 50 tables and more than 100 illustrations (half in color). Lead: Its Effects on Environment and Health is an essential resource for scientists working in the wide range from material sciences, inorganic biochemistry all the way through to medicine including the clinic... not forgetting that it also provides excellent information for teaching.

Titles of Volumes 1–44 in the Metal Ions in Biological Systems Series

edited by the SIGELs and published by Dekker/Taylor & Francis (1973–2005)

Volume 1:	Simple Complexes
Volume 2:	Mixed-Ligand Complexes
Volume 3:	High Molecular Complexes
Volume 4:	Metal Ions as Probes
Volume 5:	Reactivity of Coordination Compounds
Volume 6:	Biological Action of Metal Ions
Volume 7:	Iron in Model and Natural Compounds
Volume 8:	Nucleotides and Derivatives: Their Ligating Ambivalency
Volume 9:	Amino Acids and Derivatives as Ambivalent Ligands
Volume 10:	Carcinogenicity and Metal Ions
Volume 11:	Metal Complexes as Anticancer Agents
Volume 12:	Properties of Copper
Volume 13:	Copper Proteins
Volume 14:	Inorganic Drugs in Deficiency and Disease
Volume 15:	Zinc and Its Role in Biology and Nutrition
Volume 16:	Methods Involving Metal Ions and Complexes in Clinical Chemistry
Volume 17:	Calcium and Its Role in Biology
Volume 18:	Circulation of Metals in the Environment
Volume 19:	Antibiotics and Their Complexes
Volume 20:	Concepts on Metal Ion Toxicity
Volume 21:	Applications of Nuclear Magnetic Resonance to Paramagnetic Species
Volume 22:	ENDOR, EPR, and Electron Spin Echo for Probing Coordination Spheres
Volume 23:	Nickel and Its Role in Biology
Volume 24:	Aluminum and Its Role in Biology
Volume 25:	Interrelations Among Metal Ions, Enzymes, and Gene Expression
Volume 26:	Compendium on Magnesium and Its Role in Biology, Nutrition, and Physiology
Volume 27:	Electron Transfer Reactions in Metalloproteins
Volume 28:	Degradation of Environmental Pollutants by Microorganisms and Their Metalloenzymes
Volume 29:	Biological Properties of Metal Alkyl Derivatives
Volume 30:	Metalloenzymes Involving Amino Acid-Residue and Related Radicals
Volume 31:	Vanadium and Its Role for Life
Volume 32:	Interactions of Metal Ions with Nucleotides, Nucleic Acids, and Their Constituents
Volume 33:	Probing Nucleic Acids by Metal Ion Complexes of Small Molecules
Volume 34:	Mercury and Its Effects on Environment and Biology
Volume 35:	Iron Transport and Storage in Microorganisms, Plants, and Animals
Volume 36:	Interrelations Between Free Radicals and Metal Ions in Life Processes
Volume 37:	Manganese and Its Role in Biological Processes
Volume 38:	Probing of Proteins by Metal Ions and Their Low-Molecular-Weight Complexes
Volume 39:	Molybdenum and Tungsten. Their Roles in Biological Processes
Volume 40:	The Lanthanides and Their Interrelations with Biosystems
Volume 41:	Metal Ions and Their Complexes in Medication
Volume 42:	Metal Complexes in Tumor Diagnosis and as Anticancer Agents
Volume 43:	Biogeochemical Cycles of Elements
Volume 44:	Biogeochemistry, Availability, and Transport of Metals in the Environment

Contents of Volumes in the Metal Ions in Life Sciences Series

edited by the SIGELs

Volumes 1–4

published by John Wiley & Sons, Ltd., Chichester, UK (2006–2008)

<http://www.Wiley.com/go/mils>

<http://www.wiley.com/WileyCDA/Section/id-300350.html>

Volumes 5–9

published by the Royal Society of Chemistry, Cambridge, UK (2009–2011)
since 2015 by Walter de Gruyter GmbH, Berlin, Germany

<http://www.bioinorganic-chemistry.org/mils> <http://www.mils-WdG.com>

Volumes 10–16

published by Springer Science & Business Media BV, Dordrecht,
The Netherlands (2012–2014; MILS-10 to MILS-14)
and by Springer International Publishing AG, Cham, Switzerland
(2015–2016; MILS-15 and MILS-16)

<http://www.bioino...

Table of contents

• Cover
• Title Page
• Copyright
• ABOUT THE EDITORS
• HISTORICAL DEVELOPMENT AND PERSPECTIVES OF THE SERIES
• PREFACE TO VOLUME 17
• CONTRIBUTORS TO VOLUME 17
• TITLES OF VOLUMES 1–44 IN THE METAL IONS IN BIOLOGICAL SYSTEMS SERIES
• CONTENTS OF VOLUMES IN THE METAL IONS IN LIFE SCIENCES SERIES
• THE BIOINORGANIC CHEMISTRY OF LEAD IN THE CONTEXT OF ITS TOXICITY
• BIOGEOCHEMISTRY OF LEAD. ITS RELEASE TO THE ENVIRONMENT AND CHEMICAL SPECIATION
• ANALYTICAL METHODS FOR THE DETERMINATION OF LEAD IN THE ENVIRONMENT
• SMART CAPSULES FOR LEAD REMOVAL FROM INDUSTRIAL WASTEWATER
• LEAD SPECIATION IN MICROORGANISMS
• HUMAN BIOMONITORING OF LEAD EXPOSURE
• SOLID STATE STRUCTURES OF LEAD COMPLEXES WITH RELEVANCE FOR BIOLOGICAL SYSTEMS
• LEAD(II) COMPLEXES OF AMINO ACIDS, PEPTIDES, AND OTHER RELATED LIGANDS OF BIOLOGICAL INTEREST
• LEAD(II) BINDING IN METALLOTHIONEINS
• LEAD(II) BINDING IN NATURAL AND ARTIFICIAL PROTEINS
• COMPLEX FORMATION OF LEAD(II) WITH NUCLEOTIDES AND THEIR CONSTITUENTS
• THE ROLE OF LEAD(II) IN NUCLEIC ACIDS
• HISTORICAL VIEW ON LEAD: GUIDELINES AND REGULATIONS
• ENVIRONMENTAL IMPACT OF ALKYL LEAD(IV) DERIVATIVES: PERSPECTIVE AFTER THEIR PHASE-OUT
• LEAD TOXICITY IN PLANTS
• TOXICOLOGY OF LEAD AND ITS DAMAGE TO MAMMALIAN ORGANS
• SUBJECT INDEX