
Peroxynitrite Detection in Biological Media
Challenges and Advances
- 232 pages
- English
- PDF
- Available on iOS & Android
Peroxynitrite Detection in Biological Media
Challenges and Advances
About this book
Peroxynitrite is a powerful oxidiser which can damage a wide array of molecules within cells, including DNA and proteins, leading to apoptosis, inflammation or cancer. Peroxynitrite detection and quantification provides critical information in understanding its biological implications. Attempts to investigate the behavior of peroxynitrite in vivo and in vitro have been hampered by the difficulty in detecting this highly reactive oxygen species. This book presents the current state of the art in this research field with contributions from scientific leaders in the field. The chapters make clear the associated challenges and development for selective and sensitive detection of peroxynitrite.
This book is a timely addition to the literature, as the first in the field, dedicated to detecting this molecule in vivo. It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers.
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Information
Table of contents
- Cover
- Peroxynitrite Detection in Biological Media Challenges and Advances
- Preface
- Dedication
- Contents
- Chapter 1 - Peroxynitrite: The Basics
- Chapter 2 - Quantifying Peroxynitrite: Bridging the Gap Between Chemistry, Biology and Immunology
- Chapter 3 - Methods of Peroxynitrite Synthesis in the Context of the Development and Validation of Peroxynitrite Sensors
- Chapter 4 - Peroxynitrite-Sensitive Electrochemically Active Matrices
- Chapter 5 - Electrochemical Detection of Peroxynitrite in Biological Solutions: Challenges and Perspectives
- Chapter 6 - Real Time Monitoring of Peroxynitrite by Stimulation of Macrophages with Ultramicroelectrodes
- Chapter 7 - Electrophoretic Methods for Separation of Peroxynitrite and Related Compounds
- Chapter 8 - Investigation of PeroxynitriteâBiomembrane Interactions Using Biomimetic Interfaces
- Chapter 9 - Recent Approaches to Enhance the Selectivity of Peroxynitrite Detection
- Chapter 10 - Development of Fluorescent Probes for the Detection of Peroxynitrite
- Chapter 11 - Reversible Near-Infrared Fluorescent Probes for Peroxynitrite Monitoring
- Subject Index