The Chemistry inside Spices & Herbs: Research and Development: Volume 1
Shashi Lata, Pankaj Kumar Chaurasia
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The Chemistry inside Spices & Herbs: Research and Development: Volume 1
Shashi Lata, Pankaj Kumar Chaurasia
Informazioni sul libro
The Chemistry inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field. The book is an extensive 2-part collection of 20 chapters contributed by experts in phytochemistry with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. The contents include reviews on the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters which highlight natural drugs and their role in different diseases and special plants of clinical significance are also included. Part I focuses on the general aspects of spice biotechnology, structure activity relationships and the natural products that can be used to treat different diseases - such as neurological diseases, inflammation, pain and infections. This part also covers information about phenolic compounds, flavonoids and turmeric supplements. This book is an ideal resource for scholars (in life sciences, phytomedicine and natural product chemistry) and general readers who want to understand the importance of herbs, spices and traditional medicine in pharmaceutical and clinical research.
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Informazioni
Naturally-derived Analgesics and Anti-Inflammatory Agents
Shaimaa Fayez1, #, Mariam I. Gamal El-Din1, #, Omayma A. Eldahshan1, 2, Abdel Nasser B. Singab1, 2
Abstract
# Authors show equal contribution
* Corresponding authors Abdel Nasser B. Singab and Omayma A. Eldahshan: Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, 11566 Cairo, Egypt and Center for Drug Discovery Research and Development, Faculty of Pharmacy, Ain Shams University, Egypt; Tel: 002-010-05036231, 002-010-11841951;
E-mail: [email protected], [email protected]
INTRODUCTION
Medicinal Plant Extracts with Reported Analgesic and/or Anti-Inflammatory Activities (Table 1)
Spices/plant Name | Mechanism of Action | Refs. |
---|---|---|
Acanthus ilicifolis Linn. | In vivo analgesic effect for the chloroform and petroleum ether fractions In vitro antioxidant activity | [8] |
Ajuga laxmannii (Murray) Benth. | Inhibition of phagocytosis and decreasing the total leukocytes in vitro In vitro antioxidant activity | [9] |
Anadenanthera colubrina var. cebil (Griseb.) | In vivo anti-inflammatory potential in paw oedema model Reduction of IL-12 production and TNF-α release accompanied by elevation in IL-10 Inhibition of the production of nitric oxide | [10] |
Asphodelus microcarpus Salzm. & Viv. | Strong antioxidant capacity Reduction of the in vivo paw and ear edema induced by carrageenan and xylene | [11] |
Athyrium multidentatum (Doll.) Ching | Decreased the expression of iNOS and COX-2 enzymes Downregulation of the in vitro and in vivo mRNA expression of IL-6, IL-1β, and TNF-α | [12] |
Backhousia citriodora (Lemon myrtle) | Antioxidant properties Reduction of IL6, TNF-α, and NO levels | [13] |
Bistorta officinalis (Bistort) | Inhibition of the release of pro-inflammatory cytokines after LPS stimulation | [14] |
Boswellia species oleogum resin | Antioxidant effect Immunomodulatory effects Decreased paw edema, pleural exudates, pain, and fever in vivo. | [16] |