Sequence Alignment
Michael S. Rosenberg Ph. D., Michael S. Rosenberg Ph. D.
- 360 pagine
- English
- PDF
- Disponibile su iOS e Android
Sequence Alignment
Michael S. Rosenberg Ph. D., Michael S. Rosenberg Ph. D.
Informazioni sul libro
The sequencing of the human genome involved thousands of scientists but used relatively few tools. Today, obtaining sequences is simpler, but aligning the sequences—making sure that sequences from one source are properly compared to those from other sources—remains a complicated but underappreciated aspect of comparative molecular biology. This volume, the first to focus on this crucial step in analyzing sequence data, is about the practice of alignment, the procedures by which alignments are established, and more importantly, how the outcomes of any alignment algorithm should be interpreted. Edited by Michael S. Rosenberg with essays by many of the field's leading experts, Sequence Alignment covers molecular causes, computational advances, approaches for assessing alignment quality, and philosophical underpinnings of the algorithms themselves.