Computational and Statistical Methods for Protein Quantification by Mass Spectrometry
eBook - ePub

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

About this book

The definitive introduction to data analysis in quantitative proteomics

This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author's carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers.

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry:

  • Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs.
  • Is illustrated by a large number of figures and examples as well as numerous exercises.
  • Provides both clear and rigorous descriptions of methods and approaches.
  • Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work.
  • Features detailed discussions of both wet-lab approaches and statistical and computational methods.

With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.

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Yes, you can access Computational and Statistical Methods for Protein Quantification by Mass Spectrometry by Ingvar Eidhammer,Harald Barsnes,Geir Egil Eide,Lennart Martens in PDF and/or ePUB format, as well as other popular books in Mathematics & Probability & Statistics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Wiley
Year
2012
Print ISBN
9781119964001
eBook ISBN
9781118493779
Edition
1
Topic
Mathematics
Subtopic
Probability & Statistics
Index
Mathematics

Table of contents

  1. Cover
  2. Title Page
  3. Copyright
  4. Preface
  5. Terminology
  6. Acknowledgements
  7. Chapter 1: Introduction
  8. Chapter 2: Correlations of mRNA and protein abundances
  9. Chapter 3: Protein level quantification
  10. Chapter 4: Mass spectrometry and proteinĀ identification
  11. Chapter 5: Protein quantification by mass spectrometry
  12. Chapter 6: Statistical normalization
  13. Chapter 7: Experimental normalization
  14. Chapter 8: Statistical analysis
  15. Chapter 9: Label based quantification
  16. Chapter 10: Reporter based MS/MS quantification
  17. Chapter 11: Fragment based MS/MS quantification
  18. Chapter 12: Label based quantification by MS spectra
  19. Chapter 13: Label free quantification by MS spectra
  20. Chapter 14: Label free quantification by MS/MS spectra
  21. Chapter 15: Targeted quantification ā€“ Selected Reaction Monitoring
  22. Chapter 16: Absolute quantification
  23. Chapter 17: Quantification of post-translational modifications
  24. Chapter 18: Biomarkers
  25. Chapter 19: Standards and databases
  26. Chapter 20: Appendix A: Statistics
  27. Chapter 21: Appendix B: Clustering and discriminant analysis
  28. Bibliography
  29. Index