eBook - ePub

Diversity-Oriented Synthesis

Name: Diversity-Oriented Synthesis
ISBN: 9781118618141

Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Andrea Trabocchi,

English
ePUB (mobile friendly)
Available on iOS & Android

eBook - ePub

Diversity-Oriented Synthesis

Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Andrea Trabocchi,

About this book

Discover an enhanced synthetic approach to developing and screening chemical compound libraries

Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.

Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book:

Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles
Expands on the concept of diversity-oriented synthesis by describing chemical libraries
Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays
Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research

This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.

Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

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Yes, you can access Diversity-Oriented Synthesis by Andrea Trabocchi in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.