X2 : EVOLUTION
CONSCIOUSNESS, CONSCIENCE, AND CURE
V
MAD GENETICS: THE SINISTER SIDE OF BIOLOGICAL MASTERY
Andrew Burnett
Nathaniel Essex is a serious scientist born into a comic-book world. Toiling obsessively to prove his theories, shunned by the scientific establishment for his unorthodox experiments, he stands on the brink of enlightenment or, perhaps, corruption. A fateful encounter with Apocalypse provides both. When offered genetic knowledge from outside his own timeline, Essex accepts transformation at Apocalypseâs hands, refashioning his body and mind to eliminate mortal weaknessâand with it, his essential humanity. Casting off his identity as Essex, he becomes the diabolical figure known as Mister Sinister. In decades to come, he will emerge as a geneticist of unparalleled brilliance and daring, a witness to great discoveries and travesties of medical history, and one of the most dangerous opponents the X-Men will ever face.
The mad geneticist is a mad scientist but with a difference. Mastery of the genetic code not only unlocks the powers of nature, it confers a certain seductive ability to redraw the boundaries of human and mutant existence. Heroic scientists such as Henry McCoy, Moira MacTaggert, and Charles Xavier, although sometimes tormented by the moral weight of their choices, are mostly able to resist temptations to misuse their knowledge and power. But many others succumb out of weakness, naivetĂ©, or flawed motives, forsaking ethical restraint and leaving behind a trail of scarred, even dead, victims. Those with ordinary talent or luck often perish when their experiments get out of control. But Mister Sinister survives, driven by purposes that mystify others but burn with âthe fierce light of clarityâ in his scientific mind.1
Mister Sinister and other villainous geneticists illustrate a very real set of concerns about the moral interpretation and use of genetic knowledge, in our world as well as theirs. Even in ostensibly advanced societies, the progress of biomedicine has been shadowed by events that echo Mister Sinisterâs dark obsessions of genetic mastery. If biotechnological progress is not accompanied by ethical maturity, we may yet see more of these stories play out, exacting an awesome price in individual and global suffering.
The Burden of Dangerous Knowledge
Like the X-Men, bioethics is a child of the atom that came of age in the 1960s, outside of the cultural mainstream. Postwar revelations of Axis atrocities carried out by scientists and physicians had shaken the world. But the ongoing practice of ethically unsupervised research on vulnerable populationsâunder democratic as well as totalitarian regimesâcame only slowly to public attention. Bioethics also went against current philosophical fashion, which emphasized analysis of ethical statements (metaethics) over making actual ethical judgments (normative ethics). Despite these difficulties, bioethics began to attract a wider public and professional audience. Few could deny the expanding influence of biomedical technology or the inadequacy of existing ethical guidance and regulations.
From its beginnings, bioethics incorporated a basic insight that is amply displayed in the X-Verse: knowledge is power, and power always has a dangerous edge. Power to heal includes power to kill. Power to preserve life includes power to prolong suffering. Power to identify differences includes power to isolate and oppress those who are different. Power to read genetic information includes power to take away individualsâ freedom and responsibility. And power to reengineer humans, animals, or plants includes power to invite disaster, through hostile intent or simple miscalculation.
Ultimately, bioethics is about more than the balance of power or regulating biomedical activities relative to a given set of moral standards. Bioethics also involves wrestling with new moral questions posed by biomedical discoveries, realizing that our ethical standards appear differently as biology fills in our picture of humanity and its place in the world. This means there is a vital, if not always acknowledged, relationship between bioethics and the philosophy of biology, a difficult dialogue between the way things ought to be and the way things empirically appear to be. What is the meaning of justice and compassion in the larger life story of which humanity is only one part? On what basis would, or should, the strong feel solidarity with the vulnerable, evolutionary winners with those who are expected to lose? Should science model itself after the moral neutrality of the natural processes it studies? What happens when it does?
Nature, Red in Tooth and Claw
The rift between biology and ethics broke the surface in Victorian England, a society shaken by biological, industrial, and social revolutions. Even before Darwinâs work was published, older conceptions of the natural order of things were coming under critical pressure. Evidence for a long history of life on Earth challenged literal readings of Genesis. But the real problem was not simply chronological. Nature was revealing multiple features that were hard to reconcile with divine design, such as natural cataclysms and the extinctions of multiple species, the apparent wastefulness of many biological processes, and the cruel adaptations of âtorturing parasites, which outnumber in their kinds all other creatures.â2
A generation earlier, the arguments of William Paleyâs Natural Theology impressed educated Britons (including the young Charles Darwin) with abundant natural evidence for a benevolent Creator. But if one could reason from Nature to God, how then should one interpret the widespread suffering due to natural causes, especially diseases that afflicted children and cut short so many lives? What kind of God would that reveal? Tennysonâs âIn Memoriamâ expresses the dismay many Victorians felt:
Are God and Nature then at strife,
That Nature lends such evil dreams?
So careful of the type she seems,
So careless of the single life;
. . . . . . . . . . . . . . . . . . . . . . .
I falter where I firmly trod,
And falling with my weight of cares
Upon the great worldâs altar-stairs
That slope throâ darkness up to God,
I stretch lame hands of faith, and grope . . .3
Reaching toward a loving God but confronted by Natureâs indifference to individual suffering, it is no wonder that some Victorians began to wonder about the basis for their moral sensibilities or the possibility of using science as a weapon to rebel against the natural order, rather than meekly accepting it. These are just the questions that fire the imagination of Nathaniel Essex. The scene is London 1859, ground zero for Darwinâs Origin of Species. Like Darwin himself, Essex has been emotionally devastated by losing a child to disease (implied to be a genetic condition). Energized by Darwinâs theory, Essex gets into a heated debate with him about the potential to take control of future human evolution. Darwin counsels compassion and restraint and eventually expresses concern for Essexâs mental stability. Stung by Darwinâs rejection and devastated by his wifeâs death in premature labor, Essex rages in frustration at his own moral limitations and opens himself to the dreadful bargain offered by Apocalypse.
After his transformation, Mister Sinister exults at having âundergone what amounts to an industrial revolution of the mind,â shedding Essexâs moral restraint, which âprevented me from reaching the highest summit of knowledge.â4 Quickly rebelling against servitude to Apocalypse, he is freed to pursue his scientific agenda without interference from society or his own conscience. Like Nature, he, too, will be attentive to the typeâwhether Homo sapiens or Homo superiorâand more careless when it comes to a single life.
Evolutionary Justice?
Is Mister Sinisterâs reading of evolutionary ethics correct? Is it really true that the only moral lesson of natural selectionâif anyâis victory in the struggle for existence, at any cost? Does evolution show that loving thy neighbor is not just an illusion, but actually an obstacle to real progress in economics, politics, and especially science? Such a view is hardly a necessary component of Darwinâs theory, although it resonates with folk philosophies of biology such as âdog eat dogâ and the âlaw of the jungleâ that portray the natural world as an amoral world. But, in fact, itâs not only possible but actually quite plausible to see a more harmonious relationship between biology and morality.
Herbert Spencer (1820-1903) was not merely an intellectual cheerleader for Darwinâs theory, although it was he, not Darwin, who introduced the popular formula âsurvival of the fittest.â
He was also an ambitious moral and political thinker with a huge influence on his contemporaries. Rethinking history in evolutionary terms, he pressed a claim Darwin had only hinted at, about the need for humans to evolve morally as well as physically:
Here we shall assume it to be an inevitable inference from the doctrine of organic evolution, that the highest type of living being, no less than all lower types, must go on molding itself to those requirements which circumstances impose. And we shall, by implication, assume that moral changes are among the changes thus wrought out.5
Spencer saw a natural logic driving the development of human ethical behavior, just as it did the âquasi-ethicalâ behavior traits observed among higher animals. But the behavior patterns Spencer studied, at least among social animals, were based on the needs of the group, rather than of the individual organism. âDog eat dogâ turns out to be a losing strategy for dogkind, and even the law of the jungle includes the need to support young offspring who cannot care for themselves. Thus, instead of playing up the contrasts between biological facts and human moral feelings, Spencer encouraged the view that ethics had been, and would continue to be, shaped by a natural balance between cooperation and competition, between aggressiveness and restraint. Too little sympathy for oneâs fellow creatures could prove just as detrimental as too much.
If Spencer is right, then those who cite evolution to justify aggression and conquest are telling only part of the story. Egoists such as Mister Sinister, Apocalypse, Magneto, the Brotherhood, the Phalanx, and others may hail themselves as the next stage of evolution, agents of Natureâs will, in eradicating those who stand in their way. And a collection of totalitarian villains has attempted similar rationalizations in our world. Yet a stronger case can be madeâeven on a strictly evolutionary basisâin support of altruists like Moira MacTaggert, Colossus, Cyclops, Cable, and Charles Xavier, whose âfitnessâ is reflected in sacrificing themselves so that others may survive. Evolution may have a cruel side, yet those who justify cruelty with genetic necessity are perhaps only making excuses.
The Eugenic Agenda
Another aspect of Mister Sinisterâs agenda poses a more subtle ethical challenge. What if, instead of plotting to dominate oneâs fellow humans or mutants, the goal is to improve their lot by improving their genetic constitution and increasing the number of âsuperiorâ individuals? Does the prospect of controlling evolution in a beneficial way confer moral legitimacy on the project? Do benefits to future genetically enhanced generations justify breaking a few eggs? Sir Francis Galton (1822-1911) believed they did. Galton coined and popularized the term eugenics to describe his project of taking control of human evolution. Rather than abandoning humanity to the randomness and misery entailed in the natural evolutionary process, eugenics would take a rational and (relatively) gentle approach to ensuring biological progress:
Now that this new animal, man, finds himself somehow in existence, endowed with a little power and intelligence, he ought, I submit, to awake a fuller knowledge of his relatively great position, and begin to assume a deliberate part in furthering the great work of evolution. He may infer the course it is bound to pursue, from his observation of that which it has already followed, and he might devote his modicum of power, intelligence, and kindly feeling to render its future progress less slow and painful.6
Galton was a pioneer in the field of biometrics, devising ways to measure and quantify all manner of natural phenomena, with a special interest in human intelligence. Galton and his colleagues believed it possible to identify families and racial strains with clearly measurable variations in genetic giftedness. Working before the discovery of genetic engineering or testingâor even a basic theory of how genes work or what they are made ofâthe only âtechnologyâ available to Galton and the early eugenicists was selective breeding: maximizing reproduction among âfitâ specimens, while discouraging or preventing the âunfitâ from passing on their âinferiorâ genes.
It is easy to picture Mister Sinister, who would have been a contemporary of Galton, listening with approval to Galtonâs lecture...