Whilst this book has its roots in the highly acclaimed book of the same name, written by Stephen Curry nearly thirty years ago, it is essentially a new book having been restructured and largely rewritten. This readable and informative book is an invaluable resource for professionals and students needing to develop a rational approach to the investigation and application of drugs.
eBook - ePub
Drug Disposition and Pharmacokinetics
From Principles to Applications
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Drug Disposition and Pharmacokinetics
From Principles to Applications
About this book
This is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects. The text provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical assessment of the concentrations in plasma and body fluids. Understanding the equations requires little more than a basic knowledge of algebra, laws of indices and logarithms, and very simple calculus. A companion web site contains additional illustrations, further equations and numerous worked examples.
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Information
Table of contents
- Cover
- Title
- Copyright
- Preface
- About the Authors
- 1: Chemical Introduction: Sources, Classification and Chemical Properties of Drugs
- 2: Drug Administration and Distribution
- 3: Drug Elimination
- 4: Elementary Pharmacokinetics
- 5: More Complex and Model Independent Pharmacokinetic Models
- 6: Kinetics of Metabolism and Excretion
- 7: Further Consideration of Clearance, and Physiological Modelling
- 8: Drug Formulation: Bioavailability, Bioequivalence and Controlled-Release Preparations
- 9: Factors Affecting Plasma Concentrations
- 10: Pharmacogenetics and Pharmacogenomics
- 11: Developmental Pharmacology and Age-related Phenomena
- 12: Effects of Disease on Drug Disposition
- 13: Quantitative Pharmacological Relationships
- 14: Pharmacokinetic/Pharmacodynamic Modelling: Simultaneous Measurement of Concentrations and Effect
- 15: Extrapolation from Animals to Human Beings and Translational Science
- 16: Peptides and Other Biological Molecules
- 17: Drug Interactions
- 18: Drug Metabolism and Pharmacokinetics in Toxicology
- 19: Drug Monitoring in Therapeutics
- Appendix: Mathematical Concepts and the Trapezoidal Method
- Acknowledgements
- Index
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Yes, you can access Drug Disposition and Pharmacokinetics by Stephen H. Curry,Robin Whelpton in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biotechnology. We have over 1.5 million books available in our catalogue for you to explore.