
- 294 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
About this book
Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticleâprotein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration.
This book provides a detailed understanding of nanoparticleâprotein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticleâprotein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.
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Information
Table of contents
- Cover
- Half Title
- series Editor
- Title
- Copyright
- Preface
- Contents
- CHAPTER 1 NanoparticleâProtein Corona Complex: Composition, Kinetics, PhysicoâChemical Characterization, and Impact on Biomedical Applications
- CHAPTER 2 Biological Significance of the Nanoparticles Protein Corona
- CHAPTER 3 Factors Affecting a Nanoparticle's Protein Corona Formation
- CHAPTER 4 NPâProtein Corona Interaction: Characterization Methods and Analysis
- CHAPTER 5 An Analytical Approach to Investigate NanoparticleâProtein Corona Complexes
- CHAPTER 6 Impact of NanoparticleâProtein Interactions on Biological Assays
- CHAPTER 7 Computer Simulations for Understanding Nanoparticle-biomolecule Corona Formation
- CHAPTER 8 In Silico Approaches to Design and Characterize Peptide-based Nanostructures
- CHAPTER 9 NanomaterialâBlood Interactions: A Biomedical Perspective
- CHAPTER 10 The Protein Corona: Applications and Challenges
- Subject Index