About this book
Bioinformatics: Methods Express is unique. It is a book on bioinformatics that makes sense to non-bioinformaticians.
Bioinformatics: Methods Express helps you answer common questions such as:
*what else is similar to my gene?
*does this protein have any transmembrane regions?
*how do I visualize an alignment between these DNAs?
*where can I find specific transcription factor sequences?
The book provides the clear advice and explicit protocols that non-bioinformaticians need in order to understand what to do - and how to avoid common pitfalls. Each chapter guides you through the major databases and tools with worked examples - all accompanied by sample data files available online.
Topics covered include:
*data access
*sequence searches and alignments
*identification and annotation of features
*the transcriptome
*protein structure and function
*comparisons and phylogeny Bioinformatics: Methods Express is a comprehensive manual for all wet-bench scientists who need to use bioinformatics - from postgraduate student to principal investigator.www.scionpublishing.com/bioinformatics contains comprehensive datasets which allow the reader to practise the techniques described in the book.
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Information
Table of contents
- Contents
- Color section
- Chapter 1: Database resources for wet-bench scientists
- Chapter 2: Navigating sequenced genomes
- Chapter 3: Sequence similarity searches
- Chapter 4: Gene prediction
- Chapter 5: prediction of noncoding transcripts
- Chapter 6: Finding regulatory elements in DNA
- Chapter 7: expressed sequence tags
- Chapter 8: protein structure, classification, and prediction
- Chapter 9: Gene ontology
- Chapter 10: prediction of protein function
- Chapter 11: Multiple sequence alignment
- Chapter 12: Inferring phylogenetic relationships
- Appendix: Additional useful bioinformatic
- Index
