SECTION C ā CLINICAL APPLICATIONS
Chapter 12
Depression
Understanding depression
Depression is common. Between 5 and 10% of people seen in primary care suffer from major depression, and as many as 2ā3 times more people experience depressive symptoms but do not meet diagnostic criteria (see Box 12.1) for major depressive disorder (Katon & Schulberg, 1992).
Box 12.1
Diagnosis of major depression (DSM-IV Criteria: APA, 1994)
Five of the following criteria (including at least one of the first two criteria) must have been present almost every day for more than two weeks, and must cause significant impairment in social, occupational or other areas of functioning.
⢠Depressed mood for most of the day
⢠Reduced pleasure or interest in usual activities for most of the day
⢠Fatigue or loss of energy
⢠Substantial change in appetite or unintentional weight loss or gain
⢠Insomnia or hypersomnia
⢠Psychomotor agitation or retardation
⢠Diminished ability to think or concentrate, or indecisiveness
⢠Feelings of excessive guilt or worthlessness
⢠Recurrent thoughts of death or suicide
Cognitive-behavioural therapy for depression
CBT is the psychological treatment of choice for depression (NICE, 2009a). It is as effective as antidepressant drug therapy for major depression in primary care (Scott et al., 1997). It also has a lower rate of long-term relapse than antidepressants (Paykel et al., 1999), because patients develop lasting skills to help them cope with difficulties in life. In severe depression, a combination of CBT and antidepressants is more effective than either treatment alone.
A combined approach to depression for primary care
NICE advocates a stepped care approach to depression management, which includes psychological approaches and medication as potential treatment options in the primary care setting (Box 12.2).
Brief CBT approaches by primary care health professionals are particularly useful for patients with mild depression, for whom there is little evidence that antidepressant medication is effective. This can be carried out alongside self-help strategies, graded exercise programmes or medication if appropriate.
Box 12.2
Stepped care model (NICE, 2009a)
Focus of the intervention | Nature of the intervention |
Step 1 All known and suspected presentations of depression | Assessment, support, psycho-education, active monitoring and referral for further assessment and interventions |
Step 2 Persistent sub-threshold depressive symptoms; mild to moderate depression | Low-intensity psychological and psychosocial interventions, medication and referral for further assessment and interventions |
Step 3 Persistent sub-threshold depressive symptoms or mild to moderate depression with inadequate response to initial interventions; moderate and severe depression | Medication, high-intensity psychological interventions, combined treatments, collaborative care and referral for further assessment and interventions |
Step 4 Severe and complex depression; risk to life; severe self-neglect | Medication, high-intensity psychological interventions, electroconvulsive therapy, crisis service, combined treatments, multiprofessional and inpatient care |
Understanding depression
Typical thoughts and thinking styles in depression
Depressed people characteristically develop negative thinking patterns, which are often examples of unhelpful thinking styles (Box 12.3).
Box 12.3
Common unhelpful thinking styles in depression
⢠Black and white thinking (āI am completely uselessā)
⢠Negative, self-critical view of self (āI am such an idiotā)
⢠Ignoring positives (āNothing went well this weekā)
⢠Mind-reading (āHe thought I was boringā)
⢠Negative view of the future (āNothing will ever get any betterā) and predicting catastrophes
⢠Taking excessive personal responsibility/self-blame (āI ruined the party for everyoneā)
Depressed people tend to have self-critical and self-blaming thoughts, which lower confidence, self-esteem and cause problems in relationships with others:
āIām a terrible parent; Iām a burden to others; Iām uselessā
These thoughts are usually self-fulfilling because thinking so negatively tends to prevent people from behaving in constructive or positive ways.
Depressed people also take a negative and pessimistic view of the world. They jump to the worst conclusions and perceive others as critical, uncaring or hurtful. For example, they may focus on one minor criticism whilst ignoring a barrage of compliments.
āThe world is so full of terrible events; Nothing ever goes right for meā
Negative thinking or hopelessness about the future is common in depression, and at its most severe, can be linked with suicidal thoughts and behaviour.
āIāll never get a job ā whatās the point in trying?ā
āI will never get over this depression. Nothing will get any betterā
From theory to practiceā¦
Notice the negative thoughts displayed by depressed people. Look for negative thoughts about the self, world and future. Which unhelpful thinking styles are most common?
At this stage, do not attempt to challenge these thoughts. When you notice a negative thought, try pointing it out to the patient and empathise with the distress that the thought might cause (āIt must be very difficult to think that wayā¦ā) Then discuss the impact of thinking so negatively (āI wonder how it affects your mood to think that wayā¦?ā).
Case Example 12.1: Negative thoughts in depression
Cathy is a 26 year old bank clerk who suffers from mild depression. Here, she describes a barbecue that she attended at the weekend.
āI went to Alisonās barbecue at the weekend. I didnāt want to go, because I knew that I wouldnāt enjoy it. I never have anything interesting to say. While I was there I made a terrible mistake ā I forgot the name of Alisonās sister, Joanne. Iāve only met her once before and my mind went blank. I looked like a complete fool. I tried to make it up to her by apologising and asking abo...