Nanodispersions for Drug Delivery

Raj K. Keservani, Anil K. Sharma, Raj K. Keservani, Anil K. Sharma

• Publisher: Apple Academic Press
• Year: 2018
• Print ISBN: 9781771887014
• eBook ISBN: 9781351047548
• Edition: 1
• Topic: Medicine
• Subtopic: Pharmacology

This volume addresses efforts to overcome the shortcomings of conventional dosage forms by exploiting the principles of nanoscience to deliver drugs for medical treatment. Nanodispersions are an important aspect because they possess globules/particles in sizes usually below 1000 nm in which the drug is dispersed in a continuous medium employing surface-active agents as stabilizers. With chapters written by experienced scientists and researchers in the field, this volume provides an abundance of information on various aspects of nanodispersions for drug delivery. The book is divided into several sections: nanoemulsions, nanosuspensions, and diverse dispersed systems.

The chapters detail what nanodispersions have demonstrated in the past and what they are expoected to continue to do in the future as the technology further evolves.

Key features:

• Provides an overview of nanoemulsions for drug delivery

• Introduces the general principles, classification, and methods of preparation of nanoemulsion-based drug delivery systems

• Presents information relevant to specific routes of applications of nanoemulsions

• Looks at the various aspects of nanosuspensions, including their formulation components, preparation methods, unique features, methods of characterization, and applications in various routes of administration

• Explores nanomicellar approaches for drug delivery

• Discusses the preparation, applications, and clinical considerations of nanogels for drug delivery

CONTENTS

Dedication

About the Editors

List of Contributors

List of Abbreviations

Preface

Section I: Nanoemulsions

1. Nanoemulsions for Drug Delivery

Anudurga Gajendiran and Jayanthi Abraham

2. Nanoemulsions: Formulation Insights, Applications, and Recent Advances

Md. Rizwanullah, Javed Ahmad, Mohammad Zaki Ahmad, and Mohammed Saeed N. Algahtani

3. Nanoemulsions: Routes of Administration and Applications

Kifayat Ullah Shah, Bey Hing Goh, Learn-Han Lee, and Tahir Mehmood Khan

4. Immunomodulatory and Antimicrobial Effects of Nanoemulsions: Pharmaceutical Development Aspects And Perspectives on Clinical Treatments

Marcus Vinícius Dias-Souza, Aristides Ávilo Nascimento, and Thalles Yuri Loiola Vasconcelos

Section II: Nanosuspensions

5. Nanosuspensions: Formulation, Characterization, and Applications

M. M. Chogale, A. A. Date, V. N. Ghodake, S. A. Payghan, J. I. Disouza, and Vandana B. Patravale

6. Nanosuspensions for Drug Delivery

Kirti Rani

Section III: Diverse Dispersed Systems

7. Nanomicellar Approaches for Drug Delivery

A. S. Manjappa, P. S. Kakade, J. I. Disouza, and Vandana B. Patravale

8. Nanogels: General Characteristics, Materials, and Applications in Drug Delivery

P. R. Sarika and Nirmala Rachel James

9. Nanogels: Preparation, Applications, and Clinical Considerations

Marcos Luciano Bruschi, Fernanda Belincanta Borghi-Pangoni, Jéssica Bassi da Silva, Mariana Volpato Junqueira, and Sabrina Barbosa de Souza Ferreira

10. Polysaccharide-Based Nanogels as Drug Delivery Systems

Zahra Eskandari, Fatemeh Bahadori, and Ebru Toksoy Oner

11. Nanocapsules: Recent Approach in the Field of Targeted Drug Delivery Systems

Bhushan Rajendra Rane, Ashish S. Jain, Nayan A. Gujarathi, and Raj K. Keservani

Index

THE PRESENT BOOK IS DEDICATED TO
OUR BELOVED
AASHNA
ANIKA
ATHARVA
AND
VIHAN

ABOUT THE EDITORS

Raj K. Keservani
Raj K. Keservani, MPharm, is in the Faculty of B. Pharmacy, CSM Group of Institutions, Allahabad, India. He has more than 10 years of academic experience in various institutes of India imparting pharmaceutical education. He has published 35 peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals, 16 book chapters, 2 coauthored books, and 10 edited books. He is also active as a reviewer for several scientific international journals. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/drug delivery, health science/ life science, and biology/cancer biology/neurobiology. Mr. Keservani graduated (B. Pharmacy) from the Department of Pharmacy, Kumaun University, Nainital, Uttarakhand, India in 2005. Afterwards, he qualified GATE in same year conducted by IIT Mumbai. He received his Master of Pharmacy (M. Pharmacy) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, Madhya Pradesh, India, in 2008 with a specialization in pharmaceutics.

Anil K. Sharma
Anil K. Sharma, MPharm, PhD, is currently working as an assistant professor at the Department of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram, India. He has more than nine years of academic experience in pharmaceutical sciences. He graduated (B. Pharmacy) from the University of Rajasthan, Jaipur, India, in 2005. Afterwards, he qualified GATE in same year, conducted by IIT Mumbai. He received his Master of Pharmacy (M. Pharmacy) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, Madhya Pradesh, India, in 2007, with a specialization in pharmaceutics. He has earned his PhD from the University of Delhi. In addition, he has published 29 peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals, 15 book chapters, and 10 edited books. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), drug delivery, nanotechnology, health science/life science, and biology/cancer biology/neurobiology.

LIST OF CONTRIBUTORS

Jayanthi Abraham
Department of Biomedical Sciences, Microbial Biotechnology Laboratory, School of Bio Sciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India

Javed Ahmad
Department of Pharmaceutics, College of Pharmacy, Najran University, Kingdom of Saudi Arabia (KSA)

Mohammad Zaki Ahmad
Department of Pharmaceutics, College of Pharmacy, Najran University, Kingdom of Saudi Arabia (KSA)

Mohammed Saeed N. Algahtani
Department of Pharmaceutics, College of Pharmacy, Najran University, Kingdom of Saudi Arabia (KSA)

Fatemeh Bahadori
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Bezmialem Vakif University, Fatih 34093, Istanbul, Turkey

Fernanda Belincanta Borghi-Pangoni
Postgraduate Program in Pharmaceutical Sciences, Laboratory of Research and Development of Drug Delivery Systems, Department of Pharmacy, State University of Maringá, Maringá, Paraná, Brazil

Marcos Luciano Bruschi
Postgraduate Program in Pharmaceutical Sciences, Laboratory of Research and Development of Drug Delivery Systems, Department of Pharmacy, State University of Maringá, Maringá, Paraná, Brazil

M. M. Chogale
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga (E), Mumbai 400019, Maharashtra, India

Jéssica Bassi da Silva
Postgraduate Program in Pharmaceutical Sciences, Laboratory of Research and Development of Drug Delivery Systems, Department of Pharmacy, State University of Maringá, Maringá, Paraná, Brazil

A. A. Date
The Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA

Sabrina Barbosa de Souza Ferreira
Postgraduate Program in Pharmaceutical Sciences, Laboratory of Research and Development of Drug Delivery Systems, Department of Pharmacy, State University of Maringá, Maringá, Paraná, Brazil

Marcus Vinícius Dias-Souza
Health Sciences Faculty, University Vale do Rio Doce, Minas Gerais, Brazil

Integrated Pharmacology and Drug Interactions Research Group (GPqFAR), Brazil

J. I. Disouza
Department of Pharmaceutics, Tatyasaheb Kore College of Pharmacy, Warananagar, Panhala, Kolhapur, Maharashtra, India

Zahra Eskandari
Department of Chemistry, Biochemistry Division, Faculty of Sciences and Arts, Yildiz Technical University, Istanbul, Turkey

IBSB, Department of Bioengineering, Marmara University, Kadikoy 34722, Istanbul, Turkey

Anudurga Gajendiran
Department of Biomedical Sciences, Microbial Biotechnology Laboratory, School of Bio Sciences and Technology, VIT University, Vellore 632014, Tamil Nadu, India

V. N. Ghodake
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga (E), Mumbai 400019, Maharashtra, India

Bey Hing Goh
School of Pharmacy, Monash University, Bandar Sunway, Selangor 45700, Malaysia

Nayan A. Gujarathi
Sandip Institute of Pharmaceutical Sciences, Pune University, Nashik, India

Ashish S. Jain
Department of Pharmaceutics, Shri D. D. Vispute College of Pharmacy & Research Center, Mumbai

University, New Panvel, India

Nirmala Rachel James
Department of Chemistry, Indian Institute of Space Science and Technology (IIST), Valiamala,

Thiruvananthapuram 695547, Kerala, India

Mariana Volpato Junqueira
Postgraduate Program in Pharmaceutical Sciences, Laboratory of Research and Developmen...

Table of contents

• Cover
• Halftitle
• Title Page
• Copyright Page
• Table of Contents