Chemistry and Biochemistry of Flavoenzymes

Volume III

Franz Muller

• Publisher: CRC Press
• Year: 2019
• Print ISBN: 9781315891460
• eBook ISBN: 9781351087469
• Topic: Medicine
• Subtopic: Alternative & Complementary Medicine

Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.

Table of contents

• Cover
• Title Page
• Copyright Page
• Preface
• The Editor
• Contributors
• Table of Contents
• Chapter 1 Pyridoxine-5-P Oxidase
• Chapter 2 Xanthine Oxidase, Xanthine Dehydrogenase, and Aldehyde Oxidase
• Chapter 3 D- and L-Amino Acid Oxidases
• Chapter 4 Methanol Oxidase
• Chapter 5 Lipoamide Dehydrogenase, Glutathione Reductase, Thioredoxin Reductase, and Mercuric Ion Reductase — A Family of Flavoenzyme Transhydrogenases
• Chapter 6 Refined Three-Dimensional Structure of Glutathione Reductase
• Chapter 7 Structure and Function of Succinate Dehydrogenase and Fumarate Reductase
• Chapter 8 Three-Dimensional Structure of Medium-Chain Acyl-CoA Dehydrogenase
• Chapter 9 Glutamate Synthase
• Chapter 10 Assimilatory Nitrate Reductase
• Chapter 11 Biological Reduction and Formation of Sulfate; the Role of APS Reductase, and FAD(Iron-Sulfur)-Containing Protein
• Chapter 12 The Stereochemistry of the Prosthetic Groups of Flavoproteins
• Chapter 13 Structure and Mechanism of Spinach Glycolate Oxidase
• Chapter 14 General Properties of Flavodoxins
• Chapter 15 Structure and Redox Properties of Clostridial Flavodoxin
• Chapter 16 Biochemistry and Molecular Biology of Bacterial Bioluminescence
• Chapter 17 Acetolactate Synthase
• Chapter 18 Phthalate Dioxygenase Reductase and Related Flavin-Iron-Sulfur-Containing Electron Transferases
• Chapter 19 Nuclear Magnetic Resonance Studies on Flavoproteins
• Chapter 20 Acyl-Coenzyme A Dehydrogenases
• Index