eBook - PDF

Aquaporins in Health and Disease

Name: Aquaporins in Health and Disease
ISBN: 9781498707848

New Molecular Targets for Drug Discovery

Graca Soveral,

Soren Nielsen,

Angela Casini,

356 pages
English
PDF
Available on iOS & Android

eBook - PDF

Aquaporins in Health and Disease

New Molecular Targets for Drug Discovery

Graca Soveral,

Soren Nielsen,

Angela Casini,

About this book

Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed the importance of aquaporins in mammalian physiology and pathophysiology as well as plant and microbial biology. The studies have also shown aquaporins as potential drug targets and targets for improving crop properties.

Written by an international group of contributors at the forefront of the field, Aquaporins in Health and Disease: New Molecular Targets for Drug Discovery presents the latest research advances in aquaporins and other major intrinsic protein (MIP) channels. The first section of the book describes the general concepts of aquaporin channel function, genomic research, structure-function analysis of aquaporins and glycerol facilitators, and regulation by gating and trafficking, including yeast aquaporin regulation and function. The second section discusses the physiological and pathophysiological roles of aquaporins in humans and microbes. The final section covers the development of inhibitors of aquaporin function. The book's epilogue offers future perspectives and directions, mainly in the area of aquaporin-based diagnostics and therapeutics.

Stimulating future research on this important protein family, this book facilitates a paradigm shift in the understanding and roles of aquaporin membrane proteins in all biological settings. It encourages scientists to develop novel approaches for the treatment of human diseases based on aquaporin function or dysfunction.

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Yes, you can access Aquaporins in Health and Disease by Graca Soveral, Soren Nielsen, Angela Casini in PDF and/or ePUB format, as well as other popular books in Medicine & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.