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Sensitive Skin Syndrome
Golara Honari, Rosa Andersen, Howard L. Maibach, Golara Honari, Rosa Andersen, Howard L. Maibach
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eBook - ePub
Sensitive Skin Syndrome
Golara Honari, Rosa Andersen, Howard L. Maibach, Golara Honari, Rosa Andersen, Howard L. Maibach
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About This Book
Sensitive skin is a widely reported condition where there is subjective cutaneous hyper-reactivity to environmental factors. Progress has been made in many aspects of the background science that will help clinicians in their management of patients presenting with the condition. This new text sums up the advances in thinking on pathophysiology, classification, methods of investigation, and the different susceptibilities of different types of skin.
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Index
Page numbers followed by f and t indicate figures and tables, respectively.
A
A-α axons, 25
A-β fibers, 25, 32, 41, 100
Abnormal muscle contraction/relaxation, 46, 48
enhanced acidity and, 48
ACD, see Allergic contact dermatitis (ACD)
Acetyl-β-methylcholine chloride (vasodilators), 5, 7
Acetylcholine, 42
Acidity, enhanced, abnormal muscle contraction and, 48
Acid-sensing ion channels (ASICs), 30, 44, 198
Actin-bound myosin cross bridges, 49f
Acute dermal irritation/corrosion testing, 178–179, 178t
Acute irritants, 175
Acute irritations
vs. cumulative irritations, 91–92, 92f
AD, see Atopic dermatitis (AD)
Adenosine monophosphate-activated protein kinase, 49
A-δ fibers, 25, 27, 28, 32, 41, 42, 44
Adiponectin, 49–50, 50f, 198
ADIPOQ, 49–50, 50f, 198
Aerobic ATP synthesis, impaired, 46, 48
Afferents, 23; see also specific types
characteristics, 25t
African Americans, 39, 105, 106, 123, 127, 130
Age-related differences
potential causes, 111
self-reported sensitive skin, 109–111, 110t
sensitization responses, 108
sensory perception, 108
skin irritation responses, 108
Air pollutants, 150–151, 151t
indoor/outdoor, 150–151, 151t
persistent organic (POPs), 150
Air pollution
barrier function and, 152
defined, 150
inflammatory reactions, 152
overview, 150
oxidative stress, 151–152
skin and, 151–152, 153t–154t
Alcohol-based formulations, 196
Allergens, 5, 168, 196
Allergen-specific T cells, 169
Allergic contact dermatitis (ACD), 141–142, 145–146, 160
assessment, 169
causes, 141–142, 145–146, 160
effector phase, 169
induction phase, 168–169
in vitro t...