Integrated Molecular Evolution

Scott Orland Rogers

• Publisher: CRC Press
• Year: 2016
• Print ISBN: 9780367372811
• eBook ISBN: 9781482230925
• Topic: Biological Sciences
• Subtopic: Biology
• Index: Biological Sciences

Evolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics.

Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on:

• Evolution of the genetic code
• Mendelian genetics and population genetics
• Natural selection
• Horizontal gene transfers
• Animal development and plant development
• Cancer
• Extraction of biological molecules
• Analytical methods
• Sequencing methods and sequencing analyses
• Omics
• Phylogenetics and phylogenetic networks
• Protein trafficking
• Human genomics

More than 400 illustrations appear in this edition, doubling the number included in the first edition, and over 100 of these diagrams are now in color.

The second edition combines and integrates extensive summaries of genetics and evolutionary biology in a manner that is accessible for students at either the graduate or undergraduate level. It also provides both the basic foundations of molecular evolution, such as the structure and function of DNA, RNA and proteins, as well as more advanced chapters reviewing analytical techniques for obtaining sequences, and interpreting and archiving molecular and genomic data.

Index

Note: Page numbers followed by f and t refer to figures and tables, respectively.

2′-deoxyribonucleic acid, 147

2′-deoxyribose adenosine monophosphate, 45f

5-methylcytosine (m5C), 48f

5S rRNAs, 57, 63

transcription, 61

5′ untranslated region (5′ UTR) of mRNA, 163

6-methyladenine (m6A), 48f

8-hydroxy-guanosine (8-OH-G), 177

16S rRNA, 57

18S rRNA, 57

21st biological amino acid, 53

23S rRNA, 57

25S rRNA, 57

454 pyrosequencing, 362

NGS using, 363f

A

Ableson murine leukemia virus (A-MuLV), 309

Abl gene, 305, 309

ABO blood group genotypes, 137, 137f

Acanthamoeba Polyphaga Mimivirus (APMV), 12, 461, 471, 472f, 473

Ac element. See Activator element

Acetyl coenzyme A (acetyl-CoA), 505

Acquired immunodeficiency syndrome (AIDS), 449

Actinobacteria, 28, 243

Activator element, 205

Adenines, 47, 49, 177

Adenocarcinomas, 301

Adenosine, 203

Adenosine 5′-phosphosulfate (APS), 362

Adenosine triphosphate (ATP), 26, 42, 115, 342, 362, 528, 530

in nucleotides, 45f

synthase, 496, 502f, 503, 505, 510

A-form DNA, 45, 47f

Agarose gel electrophoresis, 324–329. See also Polyacrylamide gel electrophoresis (PAGE)

alternative methods of, 329f

DNA separated by, 325f

fundamentals of, 326f

movement of DNAs during, 330f

Agouti, 139, 139f

Agrobacterium tumefaciens, 233, 233f

Alignment algorithms, 368

Alleles, 34, 132, 303

Hardy–Weinberg equilibrium, 148–149, 149f

inheritance analysis with, 136f

in population, 148f, 150...

Table of contents

• Cover
• Half Title
• Title Page
• Copyright Page
• Table of Contents
• Preface
• Acknowledgments
• Author
• SECTION I Life and Evolution
• SECTION II Biomolecules
• SECTION III Genetics
• SECTION IV Multicellularity
• SECTION V Molecular Biology and Bioinformatic Methods
• SECTION VI Genomes
• Index