Definitions
a- prefix meaning absence of or without; example: achlorhy- di'ia
abatement to decrease; example: an abatement of symptoms of a disease
abbreviated new drug application (ANDA) established under the Drug Price Competition and Patent Term Restoration Act (1984) allowing the FDA to accept abbreviated new drug applications for generic versions of drugs first approved after 1962; safety and effectiveness data did not have to be submitted if the drug was genetically equivalent to brand name drugs already proven to be safe and effective
abdominal packs SEE laparotomy pack
abdominohysterotomy caesarean section
abduction a drawing away, as an arm or leg from the middle line of the body
aberration 1: deviation from that which is normal 2: an imperfection on an optical lens resulting in a disturbed image
abietic acid organic acid prepared by isomerization of rosin; used in the manufacture of soaps, plastics, and lacquers
abiogenesis spontaneous generation of biological cells without known biological explanation; synonym: autogenesis
abirritant an agent used to relieve irritation
ablution washing
ABO antigens innate blood group compounds important to blood typing and transfusions
abortifacient agent that induces abortion
abradant agent that scrapes or abrades
abrasion a scraping of the skin, mucous membranes, or teeth; wearing or rubbing away by friction
abrasive substance used to scrape or erode a surface; example: dental pumice
abscess pus accumulation in any part of the body
abscissa horizontal axis of a plot or graph
absolute humidity SEE humidity, absolute
absolute rate theory SEE transition state theory
absolutes 1: values or dimensions that are defined by international agreement (SEE absolute unit) 2: pure substances that have been isolated from mixtures 3: pure solvents; example: absolute alcohol
absolute temperature an expression of fundamental heat intensity; °T = °C + 273.15; synonym: degrees Kelvin
absolute unit a measurable dimension that is defined by internationally agreed-upon standards; examples: meter, kilogram, second
absolute zero a hypothetical temperature characterized by a complete absence of heat and approximately equivalent to -273.15°C or -459.67°F
absorb 1: to take in and become part of an existent whole 2: to suck up or take up (as a sponge absorbs water); to take in food and drugs from the intestinal tract
absorbance ability of a layer of a substance to absorb radiation
absorbent gauze SEE gauze
absorption 1: process of being absorbed 2: biological process by which drugs and other substances are transported across body membranes (intestines, skin, cells) 3: physicochemical process by which molecules (liquid or gaseous) are absorbed into another system such as water into a sponge or hydrogen into palladium 4: physical interception of radiant energy or sound waves
absorption, active movement of substances through a living membrane against a concentration gradient; example: an energy requiring process catalyzed by enzymes
absorption, facilitated movement of substances through membranes aided by a carrier
absorption, passive movement of substances through membranes by simple diffusion
absorption band a region in an absoiption spectrum of a substance in which the absoiptivity reaches a maximum; an inflection point in the spectrum
absorption cell vessel used to hold substances for determination of their absoiption spectra; example: cuvette used in spectrophotometry
absorption coefficient 1: absoiption of one substance or phase into another 2: a measure of the rate of decrease in the intensity of electromagnetic radiation after its passage through a particular substance 3: absorptivity of a substance
absorption ointment base an ointment base capable of absorbing and holding relatively large amounts of water; example: lanolin
abstinence denying oneself a drug or some other gratification (food, drink, sexual intercourse)
abstract 1: short synopsis of a longer article 2: that which has been separated 3: profound, fundamental concept without units of measure
abstraction 1: removal or separation of one or more ingredients from a mixture 2: a mental state characterized by a total isolation from one’s environment
acacia gum dried gummy exudate of the acacia tree, used as a suspending or emulsifying agent; synonym: gum Arabic
Academy of Pharmaceutical Research and Sciences (APRS) a subdivision of the American Pharmacists Association established to promote research in pharmacy
Academy of Pharmacy Practice and Management (APPM) a subdivision of the American Pharmacists Association, composed of pharmacists who are providing or managing the provision of pharmaceutical services directly to patients
Academy of Students of Pharmacy (ASP) a subdivision of the American Pharmacists Association, composed of pharmacy students
accelerated stability testing SEE stability testing; Arrhenius equation
acceleration rate of increase in the velocity of movement of an object or particles, usually expressed in cm/sec2
acceleration of gravity rate of increase in movement of a substance due to the attractive force of gravity; 980.665 cm/sec2
accelerin blood-coagulation factor VI; synonym: accelerator globulin
acceptance sampling a statistically based quality control procedure of selecting representative parts of a lot of pharmaceutical preparations in order to assure that the whole is correctly prepared
access a patient’s ability to obtain medical care; ease of access determined by components such as the availability of medical services and their acceptability to the patient, the location of health care facilities, transportation, hours of operation, and affordability of care, which is often a function of insurance coverage
accessories, health surgical supplies and convalescent aids; examples: wheelchairs, walkers, ostomy supplies, elastic supports
accommodation 1: to adapt 2: ability of the eye to adjust to viewing objects at different distances; effected chiefly by changes in the convexity of the crystalline lens
accreditation process whereby an association or agency grants public recognition to an organization that meets certain established qualifications or standards, as determined through initial and periodic evaluations
accredited the fulfillment of minimum standards of an officially recognized group by a college, hospital, or other organization; example: a U.S. college or school of pharmacy must be accredited by the American Council on Pharmaceutical Education
accrete process of adding new enrollees to a health plan
accretion 1: growth characterized by addition of matter to the periphery of a body 2: a growing together 3: deposition of foreign matter on the surface of an object; example: accretion of tartar on teeth
accrual basis of accounting an accounting method whereby revenues are recognized in the period when goods or services are sold and expenses are recognized in the period when the related revenue is recorded
accrued revenues revenues that have been earned or recognized but not yet received
accumulated depreciation an account that shows the sums of depreciation charges on an asset from the time it was acquired
accumulation increase in the plasma or tissue concentration of a drug
accuracy 1: a measure of the correctness of data as these correspond to the true value 2: freedom from mistake or error
acerbic 1: acidic or sour in taste 2: acidic in temper or mood
acetoacetic ester condensation a special form of Claison condensation using ethylacetate and a base such as sodium ethoxide
acetylation substitution of an organic compound with an acyl group derived from acetic acid
acetylcholine 1: acetate ester of choline 2: neurotransmitter secreted by the endings of the voluntary nervous system and the autonomic ganglia
achlorhydria absence of hydrochloric acid secretion in gastric fluid even after the administration of histamine
achymosis 1: a lack or deficiency of chyme acicular 2: shaped like a needle; needlelike
acid 1: a type of compound that contributes a proton to a chemical reaction to form a conjugate base 2: a type of compound that accepts electrons in a chemical reaction 3: a type of compound that reacts with a base 4: an electrophile 5: a substance that has a sour taste
acid, weak an organic acid that does not completely dissociate in water
acid-base balance relative concentrations of acids and bases as in an organism or a physical system
acid-base indicator a dye solution that changes color with changes in pH
acid-base pair SEE conjugate pair
acid-fast a staining property exhibited by certain bacteria that are not decolorized by mineral acids after staining with aniline dyes; example organisms: bacilli of tuberculosis and leprosy
acidifying agent substance added to lower the pH of a system under observation
acidimetry method of quantitative analysis in which the total amount of acid in a sample is determined by titration with standard base
acidity constant 1: ionization constant of a weak acid 2: pKa 3: sigma constant of the Hammett equation 4: equilibrium constant for the ionization of a weak acid in which water is included as a reactant and hydronium ion concentration is considered instead of proton concentration
acid number SEE acid value
acidophils microorganisms that grow well in a...