Contemporary Targeted Therapies in Rheumatology
eBook - PDF

Contemporary Targeted Therapies in Rheumatology

  1. 636 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Contemporary Targeted Therapies in Rheumatology

About this book

Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path

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Yes, you can access Contemporary Targeted Therapies in Rheumatology by Josef S. Smolen, Peter E. Lipsky, Josef S. Smolen,Peter E. Lipsky in PDF and/or ePUB format, as well as other popular books in Medicine & Rheumatology, Orthopedics & Prosthetics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2007
Print ISBN
9781841844848
eBook ISBN
9780203694145
Edition
1
Topic
Medicine
Subtopic
Rheumatology, Orthopedics & Prosthetics

Table of contents

  1. Front Cover
  2. Title Page
  3. Contents
  4. Contributors
  5. Chapter 1- T cells – overview – update
  6. Chapter 02
  7. Chapter 2- Pathways of T-cell costimulation
  8. Chapter 3- Regulatory T cells
  9. Chapter 4- B-cell antigen receptor signaling and autoimmunity
  10. Chapter 5- Macrophages in rheumatoid arthritis
  11. Chapter 6- Dendritic cells
  12. Chapter 7- Osteoclasts
  13. Chapter 8- Cell contact dependence of inflammatory events
  14. Chapter 9- Toll-like receptors: possible targets for novel treatments for rheumatoid arthritis
  15. Chapter 10- Cadherin-11 mediates synovial lining organization: a new therapeutic target in inflammatory arthritis
  16. Chapter 11- TNF-α
  17. Chapter 12- Update on interleukin-6
  18. Chapter 13- Interleukin-13
  19. Chapter 14- Biology of interleukin-15
  20. Chapter 15- Interleukin-17: a new target in arthritis
  21. Chapter 16- The role of interleukin-18 in inflammation
  22. Chapter 17- Interleukin-21
  23. Chapter 18- The biology of human interleukin-32
  24. Chapter 19- The interferons
  25. Chapter 20- Osteoprotegerin
  26. Chapter 21- Update: inflammatory, angiogenic, and homeostatic chemokines and their receptors
  27. Chapter 22- New developments in NF-kB
  28. Chapter 23- Roles of the JAK-STAT signaling pathways in rheumatoid arthritis
  29. Chapter 24- Suppressor of cytokine signaling (SOCS)proteins as therapeutic targets in rheumatoid arthritis
  30. Chapter 25- Wnt signaling for targeted therapies in rheumatology
  31. Chapter 26- Inflammatory mediators: update on cyclooxygenases and prostaglandin synthases
  32. Chapter 27- Complement and pregnancy loss
  33. Chapter 28- Matrix metalloproteinases
  34. Chapter 29- MMPs and ADAMs as targets for therapies in arthritis
  35. Chapter 30- Update on proinflammatory cytokine blockade in rheumatoid arthritis
  36. Chapter 31- Targeting interleukin-1 in rheumatic diseases
  37. Chapter 32- Update on targeted therapy in psoriatic arthritis
  38. Chapter 33- Spondyloarthritides
  39. Chapter 34- Early Arthritis
  40. Chapter 35- Juvenile arthritis
  41. Chapter 36- Update – systemic lupus erythematosus
  42. Chapter 37- Vasculitis
  43. Chapter 38- Myositis
  44. Chapter 39- TNF blockade in orphan rheumatic diseases
  45. Chapter 40- Overview of the safety of TNF inhibitors
  46. Chapter 41- Anti-CD20 to further targeted therapies in rheumatology
  47. Chapter 42- Targeting B-lymphocyte stimulator(BLyS) in immune-based rheumatic diseases: a therapeutic promise waiting to be fulfilled
  48. Chapter 43- Anti-CD3 antibody – a history of successful immune interventions
  49. Chapter 44- Alefacept
  50. Chapter 45- Clinical targeting of interleukin-15
  51. Chapter 46- Clinical prospects of MAPK inhibitors
  52. Chapter 47- Clinical prospects of NF-κB inhibitors to further targeted therapies in rheumatology
  53. Chapter 48- Outcomes assessment in rheumatic disease
  54. Index
  55. Back Cover