
Molecular Carcinogenesis and the Molecular Biology of Human Cancer
- 592 pages
- English
- PDF
- Available on iOS & Android
Molecular Carcinogenesis and the Molecular Biology of Human Cancer
About this book
To gain a complete overview of what is presently known about molecular carcinogenesis would prove to be a very daunting task for those not already steeped in this complex subject. Providing an in-depth summary of the molecular aspects of carcinogenesis, this text comprehensively covers chemical, radiation, and viral carcinogenesis - from animal and human test data to metabolism and DNA binding. It covers organic and metal carcinogenesis related to lung, breast, prostate, skin, liver, colon, brain, and thyroid cancers. The book explores the human implications of data regarding oncogenesis of transgenic and knockout mice and rats. It also covers the genomics and proteomics of chemoprevention, risk and exposure assessments, and regulation of carcinogens. Molecular Carcinogenesis and the Molecular Biology of Human Cancer is an ideal text for graduate courses in cancer.
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Information
Table of contents
- Front cover
- Preface
- Editors
- Contributors
- Contents
- CH 1 Carcinogens and Mutagens
- CH 2 Whole Animal Carcinogenicity Bioassays
- CH 3 Molecular Mechanisms of Action of Selected Organic Carcinogens
- CH 4 Binding of Carcinogens to DNA and Covalent Adducts and DNA Damage — PAH, Aromatic Amines, Nitro-aromatic Compounds, and Halogenated Compounds
- CH 5 Cellular Oncogenes and Carcinogenesis
- CH 6 Tumor Suppressor Genes
- CH 7 Hepatitis B, Hepatitis C, and Hepatocellular Carcinoma
- CH 8 Oncogenesis in Transgenic and Knockout Mice
- CH 9 Chemically Induced Morphological and Neoplastic Transformation in C3H/10T1/2 Cl 8 Mouse Embryo Cells
- CH 10 Radiation Carcinogenesis
- CH 11 DNA Microarrays and Computational Analysis of DNA Microarray Data in Cancer Research
- CH 12 Application of Proteomics in Basic Biological Sciences and Cancer
- CH 13 Overview of Human Cancer Induction and Human Exposure to Carcinogens
- CH 14 Complex Mixtures of Chemical Carcinogens: Principles of Action and Human Cancer1
- CH 15 Lung Cancer
- CH 16 Breast Cancer
- CH 17 Cancer of the Prostate — Mechanisms of Molecular Carcinogenesis
- CH 18 Skin Cancer: Epidemiology, Clinical Manifestations, and Genetic and Molecular Aspects
- CH 19 Cell and Molecular Biology of Cancer of the Brain
- CH 20 Thyroid Cancer: Molecular Biology and Clinical Aspects
- CH 21 Chemoprevention of Chemical Carcinogenesis and Human Cancer
- CH 22 Carcinogen Biomarkers and Exposure Assessment
- CH 23 Risk Assessment for Chemical Carcinogens
- CH 24 Prevention and Regulation Approaches to Carcinogens
- Index
- Back cover