Simulation for Designing Clinical Trials
eBook - PDF

Simulation for Designing Clinical Trials

A Pharmacokinetic-Pharmacodynamic Modeling Perspective

  1. 416 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Simulation for Designing Clinical Trials

A Pharmacokinetic-Pharmacodynamic Modeling Perspective

About this book

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation p

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Information

Publisher
CRC Press
Year
2002
Print ISBN
9780824708627
eBook ISBN
9780203910276
Edition
1
Topic
Medicine
Subtopic
Pharmacology

Table of contents

  1. Front Cover
  2. Foreword
  3. Preface
  4. Contents
  5. Contributors
  6. Chapter 1. Introduction to Simulation for Design of Clinical Trials
  7. Chapter 2. Input-Output Models
  8. Chapter 3. Defining Covariate Distribution Models for Clinical Trial Simulation
  9. Chapter 4. Protocol Deviations and Execution Models
  10. Chapter 5. Determination of Model Appropriateness
  11. Chapter 6. Computational Considerations in Clinical Trial Simulations
  12. Chapter 7. Analysis of Simulated Clinical Trials
  13. Chapter 8. Sensitivity Analysis of Pharmacokinetic and Pharmacodynamic Models in Clinical Trial Simulation and Design
  14. Chapter 9. Choice of Best Design
  15. Chapter 10. Clinical Trial Simulation (CTS)
  16. Chapter 11. Academic Perspective
  17. Chapter 12. Modeling and Simulation of Clinical Trials
  18. Chapter 13. History-Informed Perspectives on the Modeling and Simulation of Therapeutic Drug Actions
  19. Chapter 14. Evaluation of Random Sparse Sampling Designs for a Population Pharmacokinetic Study
  20. Chapter 15. Use of Modeling and Simulation to Optimize Dose-Finding Strategies
  21. Chapter 16. Model-Based Integration for Clinical Trial Simulation and Design
  22. Chapter 17. Prediction of Hemodynamic Responses in Hypertensive and Elderly Subjects from Healthy Volunteer Data
  23. Chapter 18. Assessment of QTc Interval Prolongation in a Phase I Study Using Monte Carlo Simulation
  24. Chapter 19. Optimizing a Bayesian Dose-Adjustment Scheme for a Pediatric Trial: A Simulation Study
  25. Index
  26. Back Cover

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Yes, you can access Simulation for Designing Clinical Trials by Hui Kimko, Stephen B. Duffull, Hui Kimko,Stephen B. Duffull in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over 1.5 million books available in our catalogue for you to explore.