
Textbook of Receptor Pharmacology
- 312 pages
- English
- PDF
- Available on iOS & Android
Textbook of Receptor Pharmacology
About this book
For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from a renowned course on receptor pharmacology, this text presents in-depth coverage of this rapidly expanding research area. The book combines current understanding of classical quantitative pharmacology and drug-receptor interactions with the basics of receptor structure and signal transduction mechanisms. It focuses on molecular investigation of receptor structure, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction at the cell membrane. This edition includes updated chapters on receptor structure and signal transduction by G-proteins and tyrosine kinases as well as enhancements to the quantitative treatment of drug-receptor interactions. Several chapters contain problems and worked-out solutions.
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Information
Table of contents
- Front cover
- Contents
- Preface
- Editors
- Contributors
- Section I: Drug-Receptor Interactions
- Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions
- Section II: Molecular Structure of Receptors
- Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors
- Chapter 3. The Structure of Ligand-Gated Ion Channels
- Chapter 4. Molecular Structure of Receptor Tyrosine Kinases
- Section III: Ligand-Binding Studies of Receptors
- Chapter 5. Direct Measurement of Drug Binding to Receptors
- Section IV: Transduction of the Receptor Signal
- Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and Block
- Chapter 7. G-Proteins
- Chapter 8. Signal Transduction through Protein Tyrosine Kinases
- Section V: Receptors as Pharmaceutical Targets
- Chapter 9. Receptors as Pharmaceutical Targets
- Index
- Back cover