Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition covers all aspects of chiral drugs from academic, governmental, industrial, and clinical perspectives, reflecting the many advances in techniques and methodology. Topics include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug disc

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Yes, you can access Drug Stereochemistry by Krzysztof Jozwiak, W. J. Lough, Irving W. Wainer, Krzysztof Jozwiak,W. J. Lough,Irving W. Wainer in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.

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Publisher

Year

Print ISBN

eBook ISBN

Edition

Topic

Medicine

Subtopic

Pharmacology

Front Cover
About the Editors
Contents
Contributors
Chapter 1. The early history of stereochemistry
Chapter 2. Stereochemistry—basic terms and concepts
Chapter 3. Molecular basis of chiral recognition
Chapter 4. Separation and resolution of enantiomers and their dissociable diastereomers through direct crystallization
Chapter 5. Indirect methods for the chromatographic resolution of drug enantiomers
Chapter 6. HPLC chiral stationary phases for the stereochemical resolution of enantiomeric compounds: The current state of the art
Chapter 7. Preparative and production scale chromatography in enantiomerseparations
Chapter 8. Enantioselective separations by electromigration techniques
Chapter 9. Alternative analytical techniques for determination or isolation ofdrug enantiomers
Chapter 10. Stereoselective transport of drugs
Chapter 11. Enantioselective binding of drugs to plasma proteins
Chapter 12. Clinical pharmacokinetics and pharmacodynamics of stereoisomeric drugs
Chapter 13. Regulatory perspective on the development of new stereoisomeric drugs
Chapter 14. Molecular analysis of agonist stereoisomers at b2-adrenoceptors
Chapter 15. Development of chiral drugs from a U.S. legal patentability perspective: Enantiomers and racemates
Chapter 16. The importance of chiral separations in single enantiomer patent cases
Back Cover

About this book

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Table of contents