Principles of Proteomics, Second Edition, provides a concise and user-friendly introduction to the diverse technologies used for the large-scale analysis of proteins, as well as their applications, and their impact in areas such as drug discovery, agriculture, and the fight against disease. Proteomics is a fast-advancing field in which researchers seek to capture all the proteins in the cell and characterize them in ever more detail. Principles of Proteomics has been fully updated to reflect the most recent developments in the field without losing its focus on the underlying principles. With worked examples, case studies profiling both established and emerging technologies, and further reading lists for each chapter, Principles of Proteomics is an ideal introduction for students, researchers and those working in the industry.
- 281 pages
- English
- PDF
- Available on iOS & Android
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Principles of Proteomics
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Information
Topic
MédecineSubtopic
Biochimie en médecine10
CHAPTER
1:
THE
ORIGIN
AND
SCOPE
OF
PROTEOMICS
and
color
plates).
For
both
devices,
a
population
of
mRNA
molecules
from
a
particular
source
is
reverse-transcribed
en
masse
to
form
a
representative
complex
cDNA
population.
In
the
case
of
spotted
microarrays,
a
fluoro-
phore-conjugated
nucleotide
is
included
in
the
reaction
mix
so
that
the
cDNA
population
is
universally
labeled.
In
the
case
of
oligonucleotide
chips,
the
unlabeled
cDNA
is
converted
into
a
labeled
cRNA
(complementary
Spotted
DNA
microarray
High-density
oligonucleotide
array
Sequence
selection
(b)
Gene
X
Hybridize
Hybridize
Wash
Wash
Stain
Scan
Combined
data
in
software
X
Z
Y
Scan
2
Scan
1
Image
2
Image
1
Image
2
Image
1
X
X
Y
Y
Z
Z
Gene
X
(a)
(d)
(c)
DNA
Public
database
Glass
wafer
PM
MM
RNA
1
+
fluor
Combined
image
in
software
RNA
1
+
biotin
RNA
2
+
biotin
RNA
2
+
fluor
Oligomer
synthesis
Robotic
printing
Purification
PCR
amplification
Table of contents
- Cover
- Half Title
- Title Page
- Copyright Page
- Preface to the second edition
- Acknowledgements
- Contents
- Chapter 1: The origin and scope of proteomics
- Chapter 2: Strategies for protein separation
- Chapter 3: Strategies for protein identification
- Chapter 4: Strategies for protein quantitation
- Chapter 5: The analysis of protein sequences
- Chapter 6: The analysis of protein structures
- Chapter 7: Interaction proteomics
- Chapter 8: Protein modification in proteomics
- Chapter 9: Protein microarrays
- Chapter 10: Applications of proteomics
- Glossary
- Index
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Yes, you can access Principles of Proteomics by Richard Twyman,Ph.D Cfe,George A. in PDF and/or ePUB format, as well as other popular books in Médecine & Biochimie en médecine. We have over one million books available in our catalogue for you to explore.