- 376 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Preclinical Drug Development
About this book
Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: PharmacokineticsModeling and simula
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Yes, you can access Preclinical Drug Development by Mark Rogge, David R. Taft, Mark Rogge,David R. Taft in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- Preface
- Contents
- Contributors
- Chapter 1. The Scope of Preclinical Drug Development: An INtroduction and Framework
- Chapter 2. Lead Molecule Selection: Pharmaceutical Profiling and Toxicity Assessments
- Chapter 3. Interspecies Differences in Physiology and Pharmacology: Extrapolating Preclinical Data to Human Populations
- Chapter 4. Pharmacokinetics/ADME of Small Molecules
- Chapter 5. Pharmacokinetics/ADME of Large Molecules
- Chapter 6. Preclinical Pharmacokinetic-Pharmacodynamic Modeling and Simulation in Drug Development
- Chapter 7. Formulation and Production Strategies for Enhancing Bioavailability of Poorly Absorbed Drugs
- Chapter 8. Transporters Involved in Drug Disposition, Toxicity, and Efficacy
- Chapter 9. Toxicity Evaluations, ICH Guidelines, and Current Practice
- Chapter 10. Application of Pathology in Safety Assessment
- Chapter 11. Utilizing the Preclinical Database to Support Clinical Drug Development
- Index
- Back Cover