
Nutrigenomics
- 504 pages
- English
- PDF
- Available on iOS & Android
About this book
Nutritional genomics, also referred to as nutrigenomics, is considered one of the next frontiers in the post-genomic era. This book features the latest research on the role of oxidants and dietary antioxidants in the modulation of gene expression, aging, immune function, neuroprotection, and vascular heath. It covers the relationship between oxidants, antioxidants, and gene expression, as well as new molecular techniques for the study of redox-regulated signal transduction. It summarizes the molecular mechanisms of phytochemicals and trace elements, emphasizes the impact of variations in the human genotype on individual responses to nutrients, and offers a summary of the effect of lipid and water soluble antioxidants and fatty acids on gene expression in cultured cells, laboratory animals, and humans.
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Information
Table of contents
- cover
- Series Introduction
- Preface
- About the Editors
- Contributors
- Contents
- 1 Application of Nutrigenomics Tools to Analyze the Role of Oxidants and Antioxidants in Gene Expression
- 2 Oxidative Stress and Human Genetic Variation
- 3 Analysis of Microarray Data
- 4 Oxidative Stress, Gene Expression, and Lifespan
- 5 Anti-Oxidant Modulation in Immune Function
- 6 Concentration-Dependent Gene and Protein Expressions of Neuroprotective and Neurotoxic Activities of Antioxidants, Including Nutrients
- 7 Effects of Antioxidants on Gene Expression in Endothelial Cells
- 8 Fatty Acids, Gene Expression, and Coronary Heart Disease (CHD)
- 9 Cell Regulatory Activity of Tocopherols and Tocotrienols
- 10 Molecular Analysis of the Vitamin A Biosynthetic Pathway
- 11 Molecular Mechanisms Underlaying the Health Promoting Activity of Lycopene
- 12 Cellular Redox Activity and Molecular Functions of Ascorbic Acid
- 13 Cell Signaling Properties of a-Lipoic Acid: Implications in Type 2 Diabetes
- 14 Dietary Isoflavones and Coronary Artery Disease—Proposed Molecular Mechanisms of Action
- 15 Anti-Carcinogenic Properties of Soy Isoflavones
- 16 Effect of Ginkgo biloba Extract EGb 761 on Differential Gene Expression in the Brain
- 17 Interactions of Flavonoids and Their Metabolites with Cell Signaling Cascades
- 18 Antioxidant and Gene Regulatory Properties of Procyanidins
- 19 Cell Signaling Properties of Inositol Hexaphosphate (IP6)
- 20 Modulation of Gene Expression by Dietary Iron
- 21 Dietary Selenium and Gene Expression
- 22 Modulation of Gene Expression by Dietary Zinc
- Index