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Nutrition for Brain Health and Cognitive Performance
Talitha Best, Louise Dye, Talitha Best, Louise Dye
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eBook - PDF
Nutrition for Brain Health and Cognitive Performance
Talitha Best, Louise Dye, Talitha Best, Louise Dye
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About This Book
Public awareness of the role diet plays in brain function has been steadily increasing. This has led to significant development of new products, dietary supplements, functional foods, nutraceuticals and public health recommendations for maintaining brain function. Nutrition for Brain Health and Cognitive Performance presents a detailed and innovati
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41
3
Genetics
of
Brain
and
Cognition
and
Their
Interactions
with
Dietary
and
Environmental
Factors
Jose
M.
Ordovas
SUMMARY
Genetic,
epigenetic
and
dietary
factors
and
their
interactions
play
a
major
role
in
brain
development
and
the
balance
between
its
health
and
disease
status.
The
dramatic
developments
in
genomic
and
neuroimaging
techniques
are
enabling
researchers
to
study
these
interactions
with
new
breadth
and
depth.
This
chapter
provides
a
definition
of
key
terms
used
to
examine
the
relationship
between
genet-
ics,
diet,
metabolism
and
brain
function.
Both
TCF7L2
and
APOE
will
be
discussed
and
current
knowledge
regarding
genetics
and
brain
architecture
and
function
will
be
reviewed.
CONTENTS
Summary
..................................................................................................................
41
3.1
Introduction
....................................................................................................
42
3.2
Genes
Related
to
Brain
Architecture
and
Function
........................................
43
3.3
Gene–Diet
Interactions
Related
to
Brain
Structure,
Function
and
Cognitive
Decline
...........................................................................................
55
3.4
Brain-Derived
Neurotrophic
Factor
Gene,
a
Missing
Candidate
from GWAS
..................................................................................................
61
3.5
TCF7L2
Gene:
Association
with
Diabetes
and
Stroke
and
Modulation
by
Diet
.............................................................................................................
62
3.6
Epigenomics,
Brain
and
Cognition
.................................................................
63
3.7
Concluding
Summary
.....................................................................................
64
References
................................................................................................................
66