- 440 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
About this book
This source expertly examines the discovery, biological structure, control, and continued clarification of endotoxin from a parenteral manufacturing perspective, with in-depth discussion of state-of-the-art technologies involving Limulus amebocyte lysate (LAL) such as assay development, automation, depyrogenation. Completely revised and exp
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Yes, you can access Endotoxins by Kevin L. Williams in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front cover
- Preface
- Contents
- Contributors
- Chapter 1. Historical and Emerging Themes
- Chapter 2. Endotoxin Relevance and Control Overview
- Chapter 3. Fever and the Host Response
- Chapter 4. Endotoxin Structure, Function, and Activity
- Chapter 5. Descent of Limulus: Arthropoda and the New Biology
- Chapter 6. Microbial Biodiversity and Lipopolysaccharide Heterogeneity: from Static to Dynamic Models
- Chapter 7. Nonendotoxin Microbial Pyrogens: Lesser Endotoxins and Superantigens
- Chapter 8. Risk Assessment in Parenteral Manufacture
- Chapter 9. Endotoxin as a Standard
- Chapter 10. Mechanism, and Application
- Chapter 11. Development, Validation, and Regulation
- Chapter 12. The Pyrogen Test
- Chapter 13. Pyrogenicity Case Studies
- Chapter 14. Developing Specifications for Active Pharmaceutical Ingredients, Excipients, Raw Materials, Sterile Pharmacy Compounds, and Nutritional Supplements
- Chapter 15. Depyrogenation Validation, Pyroburden, and Endotoxin Removal
- Chapter 16. Automation, Process Analytical Technology, and Prospective Testing
- Chapter 17. Limulus Amebocyte Lysate Testing of Medical Devices
- Chapter 18. Receptors, Mediators, and Mechanisms Involved in Bacterial Sepsis and Septic Shock
- Index