| Table 1.1 A brief timeline of the history of goiter and our understanding of it |
| Time | Description |
| 2600 bc | Goiter is known in Chinaātreated with burnt sponge, seaweed, and animal thyroid. |
| 1400 bcā400 ad | Ayurvedic (traditional Indian) medicine in India provides detailed descriptions of galaganda (goiter) |
| 460 bcā375 bc | āā¦when glands of the neck become diseased themselves, they become tubercular and produce strumaā¦ā āDe Glandulis, Hippocrates |
| 23 bcā79 ad | āā¦Only men and swine are subject to swellings of the throat, which are mostly caused by the noxious quality of the water they drinkā¦ā āGaius Plinius Secundus of Pliny |
| 130ā210 ad | Galen of Pergamon describes āmutismā and āsemi-mutismā as complications of (thyroid) surgery by way of scraping with a fingernail, ātubercularā nodes. |
| 340 ad | Ko-Hung, famous Chinese alchemist, recommends seaweed for treatment of goiter for people living in mountainous regions. |
| 550 ad | Aƫtius of Amida describes exophthalmic goiter and recognizes the importance of preservation of the vocal nerves (recurrent laryngeal nerve) for phonation. |
| ā¼950ā960 ad | Abu al-Qasim al-Zahrawi (Albucasis)āconsidered to be the greatest surgeon of the middle agesāfirst describes the thyroidectomy procedure and needle biopsies for goiter. |
| 1170 ad | Roger of Palermo describes treatment of goiter with ashes of sponges and seaweed. |
| ā¼1250 ad | The Bamberg Surgery (surgical textbook) provides a detailed description of surgical thyroidectomy. |
| 1475 ad | Chinese physician Wang Hei describes treatment of goiter with minced/powdered animal thyroid. |
| 1500 ad | Leonardo da Vinci first illustrates the thyroid gland. |
| ā¼1540 ad | Bartholomew Eustachius first describes the isthmus of the thyroid gland. |
| 1543 ad | Andreas Vesalius first provides anatomic description and illustration of the thyroid gland. |
| ā¼1650 ad | Thomas Wharton provides the modern name, thyroid, after the shape of an ancient Greek shield. |
| 1811 ad | Bernard Courtois discovers iodine. |
| 1820 ad | Jean Francois Coindet describes iodine deficiency as the cause for goiter and begins treatment with iodine. |
| 1829 ad | J. G. A. Lugol recommends aqueous iodine for the treatment of goiter. |
| 1831 ad | Francisco Freire-Allemao (Brazil) proposes iodine prophylaxis to prevent goiter on a government administered, public health basis. |
| 1835 ad | Robert Graves describes a syndrome of palpitations, goiter, and exophthalmos in three women. |
| 1862 ad | Armand Trousseau introduces the term Gravesā disease. |
| 1883 ad | Emil Theodor Kocher describes myxedema as a complication of total thyroidectomy. |
| 1909 ad | Emil Theodor Kocherāconsidered the father of modern thyroid surgeryāreceives the Nobel Prize for his work on thyroid... |