Handbook of Adaptive Designs in Pharmaceutical and Clinical Development
eBook - PDF

Handbook of Adaptive Designs in Pharmaceutical and Clinical Development

  1. 496 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Handbook of Adaptive Designs in Pharmaceutical and Clinical Development

About this book

In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development provides a comprehensive and unified presentation of the princip

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Yes, you can access Handbook of Adaptive Designs in Pharmaceutical and Clinical Development by Annpey Pong,Shein-Chung Chow in PDF and/or ePUB format, as well as other popular books in Mathematics & Probability & Statistics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2016
Print ISBN
9781439810163
eBook ISBN
9781439810170
Edition
1
Topic
Mathematics
Subtopic
Probability & Statistics
Index
Mathematics

Table of contents

  1. Front cover
  2. Contents
  3. Preface
  4. Editors
  5. Contributors
  6. Chapter 1. Overview of Adaptive Design Methods in Clinical Trials
  7. Chapter 2. Fundamental Theory of Adaptive Designs with Unplanned Design Change in Clinical Trials with Blinded Data
  8. Chapter 3. Bayesian Approach for Adaptive Design
  9. Chapter 4. The Impact of Protocol Amendments in Adaptive Trial Designs
  10. Chapter 5. From Group Sequential to Adaptive Designs
  11. Chapter 6. Determining Sample Size for Classical Designs
  12. Chapter 7. Sample Size Reestimation Design with Applications in Clinical Trials
  13. Chapter 8. Adaptive Interim Analyses in Clinical Trials
  14. Chapter 9. Classical Dose-Finding Trial
  15. Chapter 10. Improving Dose-Finding: A Philosophic View
  16. Chapter 11. Adaptive Dose-Ranging Studies
  17. Chapter 12. Seamless Phase I/II Designs
  18. Chapter 13. Phase II/III Seamless Designs
  19. Chapter 14. Sample Size Estimation/Allocation for Two-Stage Seamless Adaptive Trial Designs
  20. Chapter 15. Optimal Response-Adaptive Randomization for Clinical Trials
  21. Chapter 16. Hypothesis-Adaptive Design
  22. Chapter 17. Treatment Adaptive Allocations in Randomized Clinical Trials: An Overview
  23. Chapter 18. Integration of Predictive Biomarker Diagnostics into Clinical Trials for New Drug Development
  24. Chapter 19. Clinical Strategy for Study Endpoint Selection
  25. Chapter 20. Adaptive Infrastructure
  26. Chapter 21. Independent Data Monitoring Committees
  27. Chapter 22. Targeted Clinical Trials
  28. Chapter 23. Functional Genome-Wide Association Studies of Longitudinal Traits
  29. Chapter 24. Adaptive Trial Simulation
  30. Chapter 25. Efficiency of Adaptive Designs
  31. Chapter 26. Case Studies in Adaptive Design
  32. Chapter 27. Good Practices for Adaptive Clinical Trials
  33. Back cover