
eBook - PDF
Handbook of Statistics in Clinical Oncology
- 658 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Handbook of Statistics in Clinical Oncology
About this book
Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials. Accessible to statisticians in clinical trials as well as oncologists interested in clinical trial methodology, the book presents up-to-date statistical approaches to the design and analysis of oncology clinical trials. New topics in this edition include trial designs for targeted agents, Bayesian trial design, and the inclusion of high-dimensional data and imaging techniques. This edition also contains numerous figures and examples to better explain concepts.
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Yes, you can access Handbook of Statistics in Clinical Oncology by John Crowley, Antje Hoering, John Crowley,Antje Hoering in PDF and/or ePUB format, as well as other popular books in Mathematics & Probability & Statistics. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front Cover
- Contents
- Preface
- Editors
- Contributors
- Chapter 1: Choosing a Phase I Design
- Chapter 2: Dose-Finding Designs Based on the Continual Reassessment Method
- Chapter 3: Pharmacokinetics in Clinical Oncology : Statistical Issues
- Chapter 4: Statistics of Phase 0 Trials
- Chapter 5: CRM Trials for Assessing Toxicity and Efficacy
- Chapter 6: Seamless Phase I/II Trial Design for Assessing Toxicity and Efficacy for Targeted Agents
- Chapter 7: Overview of Phase II Clinical Trials
- Chapter 8: Designs Based on Toxicity and Response
- Chapter 9: Designs Using Time-to-Event Endpoints/Single-Arm versus Randomized Phase II Designs
- Chapter 10: Phase II Selection Designs
- Chapter 11: Phase II with Multiple Subgroups : Designs Incorporating Disease Subtype or Genetic Heterogeneity
- Chapter 12: Phase II/III Designs
- Chapter 13: Use of Covariates in Randomization and Analysis of Clinical Trials
- Chapter 14: Factorial Designs with Time-to-Event Endpoints
- Chapter 15: Early Stopping of Clinical Trials
- Chapter 16: Noninferiority Trials
- Chapter 17: Phase III Trials for Targeted Agents
- Chapter 18: Adaptive Trial Designs
- Chapter 19: Design of a Clinical Trial for Testing the Ability of a Continuous Marker to Predict Therapy Benefit
- Chapter 20: Software for Design and Analysis of Clinical Trials
- Chapter 21: Cure-Rate Survival Models in Clinical Trials
- Chapter 22: Design and Analysis of Quality-of-Life Data
- Chapter 23: Economic Analyses alongside Cancer Clinical Trials
- Chapter 24: Structural and Molecular Imaging in Cancer Therapy Clinical Trials
- Chapter 25: Prognostic Factor Studies
- Chapter 26: Predictive Modeling of Gene Expression Data
- Chapter 27: Explained Variation and Explained Randomness for Proportional Hazards Models
- Chapter 28: Prognostic Groups by Tree-Based Partitioning and Data Refinement Methods
- Chapter 29: Risk Calculators
- Chapter 30: Developing a Score Based upon Gene Expression Profiling and Validation
- Chapter 31: Analysis of DNA Microarrays
- Chapter 32: Methods for SNP Regression Analysis in Clinical Studies : Selection, Shrinkage, and Logic
- Chapter 33: Forensic Bioinformatics
- Insert
- Back Cover