Adaptive Design Methods in Clinical Trials
eBook - PDF

Adaptive Design Methods in Clinical Trials

  1. 374 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Adaptive Design Methods in Clinical Trials

About this book

With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA's recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and regulatory positions on the use of adaptive designs in clini

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Yes, you can access Adaptive Design Methods in Clinical Trials by Shein-Chung Chow,Mark Chang in PDF and/or ePUB format, as well as other popular books in Medicine & Biostatistics. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2011
Print ISBN
9781439839874
eBook ISBN
9781439839881
Edition
2
Topic
Medicine
Subtopic
Biostatistics

Table of contents

  1. Front Cover
  2. Contents
  3. Preface to the First Edition
  4. Preface
  5. 1. Introduction
  6. 2. Protocol Amendment
  7. 3. Adaptive Randomization
  8. 4. Adaptive Hypotheses
  9. 5. Adaptive Dose-Escalation Trials
  10. 6. Adaptive Group Sequential Design
  11. 7. Statistical Tests for Seamless Adaptive Designs
  12. 8. Adaptive Sample Size Adjustment
  13. 9. Two-Stage Adaptive Design
  14. 10. Adaptive Treatment Switching
  15. 11. Bayesian Approach
  16. 12. Biomarker Adaptive Trials
  17. 13. Target Clinical Trials
  18. 14. Sample Size and Power Estimation
  19. 15. Clinical Trial Simulation
  20. 16. Regulatory Perspectives - A Review of FDA Draft Guidance
  21. 17. Case Studies
  22. Bibliography