DNA and RNA Modification Enzymes
eBook - PDF

DNA and RNA Modification Enzymes

Structure, Mechanism, Function and Evolution

  1. 682 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

DNA and RNA Modification Enzymes

Structure, Mechanism, Function and Evolution

About this book

This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a shortconclusion and future prospect' section and

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Yes, you can access DNA and RNA Modification Enzymes by Henri Grosjean in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
CRC Press
Year
2009
Print ISBN
9781587063299
eBook ISBN
9781498713153
Edition
1
Topic
Biological Sciences
Subtopic
Biology
Index
Biological Sciences

Table of contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Dedication
  5. Editor
  6. Contributors
  7. Contents
  8. Preface
  9. Acknowledgements
  10. 1. Nucleic Acids Are Not Boring Long Polymers of Only Four Types of Nucleotides: A Guided Tour
  11. 2. DNA Methyladon: From Bug to Beast
  12. 3. DNA Restriction-Modification Systems in Prokaryotes
  13. 4. Experimental Approaches to Study DNA Base Flipping
  14. 5. Molecular Modeling of Base Flipping in DNA
  15. 6. M-Hhal and M*EcoRI: Paradigms for Understanding the Conformational Mechanisms of DNA Methyltransferases
  16. 7. Mechanism and Evolution of DNA Recognition by DNA-(adenine N6)-Methyltransferases from the EcoDam Family
  17. 8. Structures and Activities of Mammalian DNA Methyl transferases
  18. 9. DNA Methylation and Human Diseases: An Overview
  19. 10. Expanding the Chemical Repertoire of DNA Methyltransferases by Cofactor Engineering
  20. 11. Studying Antibody MaturationUsing Techniques for Detecting Uracils in DNA
  21. 12. Enzymatic Formation of the Hypermodified DNA Base J (β-D-Glucopyranosyloxymethyluracil)
  22. 13. DNA Demethyladon
  23. 14. Demethylation of DNA and RNA by AlkB Proteins
  24. 15. The APOBEC1 Paradigm for Mammalian Cyddine Deaminases That Edit DNA and RNA
  25. 16. Mechanism of Action and Structural Aspects o f ADARS (A-to-I) and APOBEC-Related (C-to-U) Deaminases
  26. 17. Structure of RNA Editing Substrates and Their Recognition by RNA Base Deaminase
  27. 18. Biological Roles of ADARs
  28. 19. The Interplay between RNA and DNA Modifications: Back to the RNA World
  29. 20. Folate-Dependent Ihymidylate-Forming Enzymes: Parallels between DNA and RNA Metabolic Enzymes and Evolutionary Implications
  30. 21. Folds and Functions of Domains in RNA Modification Enzymes
  31. 22. Enzyme-RNA Substrate Recognition in RNA-Modifying Enzymes
  32. 23. Molecular Basis of tRNA Processing Reactions
  33. 24. RNA-Modifying Metalloenzymes
  34. 25. Pseudouridine Formation, the Most Common Transglycosylation in RNA
  35. 26. Enzymatic Formation of the 7-Deazaguanosine Hypermodified Nucleosides of tRNA
  36. 27. Biogenesis and Functions of Thio-Compounds in Transfer RNA: Comparison of Bacterial and Eukaryotic Ihiolation Machineries
  37. 28. Enzymatic Formation of 5-Aminomethyl-Uridine Derivatives in tRNA: Functional and Evolutionary Im plications
  38. 29. Deciphering the Complex Enzymatic Pathway for Biosynthesis of Wyosine Derivatives in Anticodon of tRNAphe
  39. 30. Multicomponent 2'-0-Ribose Methylation Machines: Evolving Box C /D RNP Structure and Function
  40. 31. Multicomponent Machines in RNA Modification: H/ACA Ribonucleoproteins
  41. 32. Spliceosomal snRNA Pseudouridylation
  42. 33. Transfer RNA Aminoacylation and Modified Nucleosides
  43. 34. Crystallographic Studies of Decoding by Modified Bases: Correlation of Structure and Function
  44. 35. Roles of the Ultra-Conserved Ribosomal RNA Methyltransferase KsgA in Ribosome Biogenesis
  45. 36. Antibiotic Resistance in Bacteria through Modification of Nucleosides in 16S Ribosomal RNA
  46. 37. Antibiotic Resistance in Bacteria Caused by M odified Nucleosides in 23S Ribosomal RNA
  47. 38. Function of Modified Nucleosides in RNA Stabilization
  48. 39. Roles of tRNA Modifications in tRNA Turnover
  49. 40. The “PACE'' Concept Pointed at New Key Proteins Involved in RNA Metabolism
  50. 41. Chemical Synthesis of DNA and RNA Containing Modified Nucleotides
  51. Appendix 1: Chemical Structures, Classification of Modified Nucleosides in RNA and the MODOMICS Database Concerning the Corresponding RNA Modification Enzymes
  52. Appendix 2: Databases of DNA Modifications
  53. Appendix 3: RNA Modification Subsystems in the SEED Database
  54. Appendix 4: List of Available Phosphoramidites of Modified Nucleotides for Chemical DNA/RNA Synthesis
  55. Appendix 5: S-Adenosyl-L-Methionine and Analogs
  56. Appendix 6: Web Links to Databases about RNA and DNA Modifications and Related Topics
  57. Index