- 256 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
High-Throughput Lead Optimization in Drug Discovery
About this book
A Single Source on Parallel Synthesis for Lead Optimization
The end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high qualit
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Yes, you can access High-Throughput Lead Optimization in Drug Discovery by Tushar Kshirsagar in PDF and/or ePUB format, as well as other popular books in Medicine & Biotechnology in Medicine. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Front cover
- Contents
- Preface
- Contributors
- Chapter 1. Introduction and Review
- Chapter 2. Application of Parallel Synthesis to the Optimization of Inhibitors of the ZipA-FtsZ ProteināProtein Interaction
- Chapter 3. Case Studies of Parallel Synthesis in Hit Identification, Hit Exploration, Hit-to- Lead, and Lead Optimization Programs
- Chapter 4. A Successful Application of Parallel Synthesis to Computer-Assisted Structural Optimization of New Leads Targeting Human Immunodeficiency Virus-1 Reverse Transcriptase: The Case of Acylthiocarbamates
- Chapter 5. How High-Throughput Medicinal Chemistry Can Expedite Lead Discovery, Lead Optimization, and Beyond
- Chapter 6. Rapid Lead Identification of Inhibitors of Adenine Nucleotide Translocase: A Case Study of Applying Combinatorial Chemistry Techniques in Drug Discovery
- Chapter 7. Parallel Synthesis of Anticancer, Antiinflammatory, and Antiviral Agents Derived from L-and D-Amino Acids
- Chapter 8. Application of Solid-Phase Parallel Synthesis in Lead Optimization Studies
- Chapter 9. High-Throughput Solid-Phase Synthesis of Nucleoside- Based Libraries in the Search for New Antibiotics
- Index
- Back cover