Approaches to the Conformational Analysis of Biopharmaceuticals
eBook - PDF

Approaches to the Conformational Analysis of Biopharmaceuticals

  1. 366 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Approaches to the Conformational Analysis of Biopharmaceuticals

About this book

The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches to analysis exists, finding the most viable ones wou

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Yes, you can access Approaches to the Conformational Analysis of Biopharmaceuticals by Roger L. Lundblad in PDF and/or ePUB format, as well as other popular books in Medicine & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
Chapman and Hall/CRC
Year
2009
eBook ISBN
9781439807811
Edition
1
Topic
Medicine
Subtopic
Biochemistry in Medicine

Table of contents

  1. Front cover
  2. Contents
  3. Series Preface
  4. Preface
  5. Author
  6. Chapter 1. Introduction to Biopharmaceutical Conformational Analysis: Issues and Methods
  7. Chapter 2. Comparability of Biotechnological/ Biological Products and Biological Generics
  8. Chapter 3. Application of Native Electrophoresis for the Study of Protein Conformation
  9. Affinity Chromatography Including Hydrophobic Interaction Chromatography in the Study of Biopolymer Conformation
  10. Chapter 5. Size-Exclusion Chromatography and Biomolecular Conformation
  11. Chapter 6. Use of Analytical Ultracentrifugation to Study Biomolecular Conformation
  12. Chapter 7. Use of Differential Scanning Calorimetry to Measure Conformational Change in Proteins and Other Biomacromolecules
  13. Chapter 8. Light Scattering and Biomacromolecular Conformation
  14. Chapter 9. Use of Luminescence to Measure Conformational Change in Biopharmaceuticals with Emphasis on Protein and Protein Drug Products
  15. Chapter 10. Near-Infrared Spectroscopy and Macromolecular Conformation
  16. Chapter 11. Use of Mid-Infrared and Fourier Transform Infrared Spectroscopy to Study Conformation of Biomacromolecules
  17. Chapter 12. Use of Raman Spectroscopy to Evaluate Biopharmaceutical Conformation
  18. Chapter 13. Use of UV-VIS Spectrophotometry for the Characterization of Biopharmaceutical Products
  19. Chapter 14. Use of Optical Rotatory Dispersion and Circular Dichroism to Study Therapeutic Biomacromolecule Conformation
  20. Chapter 15. Use of Nuclear Magnetic Resonance for the Characterization of Biotherapeutic Products
  21. Chapter 16. Use of Chemical Probes for the Study of Protein Conformation
  22. Chapter 17. Use of Hydrogen Exchange in the Study of Biopharmaceutical Conformation
  23. Chapter 18. Use of Chemical Modification for the Conformational Analysis of Biopharmaceuticals
  24. Chapter 19. Use of Immunology to Characterize Biopharmaceutical Conformation
  25. Chapter 20. Use of Limited Proteolysis to Study the Conformation of Proteins of Biotechnological Interest
  26. Chapter 21. Other Technologies for the Characterization of Conformational Change in Biopharmaceuticals
  27. Chapter 22. Development of an Experimental Approach for the Study of the Conformation of a Biological Therapeutic Product
  28. Index
  29. Back cover