- 848 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
About this book
This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes. It presents strategies for creating a wide variety of compounds for drug discovery and analyzes peptides, DNA, carbohydrates,
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Yes, you can access Solid-Phase Synthesis by Fernando Albericio in PDF and/or ePUB format, as well as other popular books in Medicine & Biochemistry in Medicine. We have over one million books available in our catalogue for you to explore.
Information
Table of contents
- Cover
- Half Title
- Title Page
- Copyright Page
- Foreword
- Preface
- Contents
- Contributors
- Introduction: The Impact of Genome Sequencing on Drug Discovery
- 1: The Solid Support
- 2: Strategy in Solid-Phase Peptide Synthesis
- 3: Amino Acids: Alpha-Amino Protecting Groups
- 4: Side-Chain Protecting Groups
- 5: Solid Supports for the Synthesis of Peptides and Small Molecules
- 6: Coupling Methods: Solid-Phase Formation of Amide and Ester Bonds
- 7: Homodetic Cyclic Peptides
- 8: Disulfide Formation in Synthetic Peptides and Proteins: The State of the Art
- 9: Solid-Phase Convergent Approaches to the Synthesis of Native Peptides and Proteins
- 10: Preparation of Glyco-, Phospho-, and Sulfopeptides
- 11: Oligonucleotide Synthesis
- 12: Synthesis of Oligonucleotide-Peptide Conjugates and Nucleopeptides
- 13: The Chemistry of Peptide Nucleic Acids
- 14: Solid-Phase Synthesis of Oligosaccharides
- 15: Solid-Phase Synthesis of Heterocyclic Compounds from Amino Acids and Linear Peptides
- 16: Solid-Phase Synthesis of Pseudopeptides and Oligomeric Peptide Backbone Mimetics
- 17: Instrumentation
- 18: The Purification of Synthetic Peptides
- 19: Analysis of Synthetic Peptides
- 20: The Chromatographic Analysis of Combinatorial Arrays: Parallel HPLC and HPLC-MS
- Index