RNA-Based Regulation in Human Health and Disease
eBook - ePub

RNA-Based Regulation in Human Health and Disease

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  1. 444 pages
  2. English
  3. ePUB (mobile friendly)
  4. Available on iOS & Android
eBook - ePub

RNA-Based Regulation in Human Health and Disease

,

About this book

RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics.- Comprehensive information of non-canonical RNA-based genome regulation modulating human health and disease- Defines RNA classes with special emphasis on unexplored world of noncoding RNA at different hierarchies- Disease specific role of RNA - causal, prognostic, diagnostic and therapeutic- Features contributions from leading experts in the field

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Information

Table of contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Translational Epigenetics Series
  5. Copyright
  6. Artist Biography
  7. Chapter 1. Introduction
  8. Chapter 2. Non-coding RNAs: ever-expanding diversity of types and functions
  9. Chapter 3. Functional categories of RNA regulation
  10. Chapter 4. The dynamic aspects of RNA regulation
  11. Chapter 5. RNA beyond humans
  12. Chapter 6. Extracellular RNA in human health and disease
  13. Chapter 7. RNA and malaria pathogenesis
  14. Chapter 8. RNA and metabolic disorders
  15. Chapter 9. RNA toxicity in tandem nucleotide repeats mediated neurodegenerative disorders
  16. Chapter 10. Regulation by non-coding RNAs in respiratory disorders
  17. Chapter 11. RNA in cancer
  18. Chapter 12. RNA and inflammatory autoimmune diseases
  19. Chapter 13. RNA and bacterial infection
  20. Chapter 14. RNA and stress
  21. Chapter 15. RNA and aging
  22. Chapter 16. Experimental toolkit to study RNA level regulation
  23. Chapter 17. Industry perspective
  24. Chapter 18. Summary and future perspectives
  25. Index