Applications of NMR Spectroscopy: Volume 2

Atta-ur Rahman,M. Iqbal Choudhary

• Publisher: Bentham Science Publishers
• Year: 2015
• ISBN:
  9781608059652
• Topic: Physical Sciences
• Subtopic: Spectroscopy & Spectrum Analysis

Applications of NMR Spectroscopy, Volume 2, originally published by Bentham and now distributed by Elsevier, presents the latest developments in the field of NMR spectroscopy, including the analysis of plant polyphenols, the role of NMR spectroscopy in neuroradiology, NMR–based sensors, studies on protein and nucleic acid structure and function, and mathematical formations for NMR spectroscopy in structural biology.

The fully illustrated chapters contain comprehensive references to the recent literature. The applications presented cover a wide range of the field, such as drug development, medical imaging and diagnostics, food science, mining, petrochemical, process control, materials science, and chemical engineering, making this resource a multi-disciplinary reference with broad applications.

The content is ideal for readers who are seeking reviews and updates, as it consolidates scientific articles of a diverse nature into a single volume. Sections are organized based on disciplines, such as food science and medical diagnostics. Each chapter is written by eminent experts in the field.

• Consolidates the latest developments in NMR spectroscopy into a single volume
• Authored and edited by world-leading experts in spectroscopy
• Features comprehensive references to the most recent related literature
• More than 65 illustrations aid in the retention of key concepts

Section A

Food sciences

Chapter 1

Application of NMR Spectroscopy in Plant Polyphenols Associated with Human Health

Ziaullah; H.P. Vasantha Rupasinghe* Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, P.O. Box 550, Nova Scotia B2N 5E3, Canada

Abstract

Polyphenols have been recognized as one of the largest and most widespread groups of plant secondary metabolites with marked antioxidant properties as well as recently recognized specific biological properties associated with prevention of chronic diseases such as cardiovascular disease, various cancers and type II diabetes. Within plant kingdom, over 50,000 of structurally diverse polyphenols are present, and their characterization stands as a challenge. In recent years, renewed interest in extraction, isolation and identification of polyphenols especially flavonoids from plant sources have become the core research in food chemistry, pharmacognosy and modern medicinal biochemistry. The NMR spectroscopy, which provides a rapid and nondestructive method for profiling of polyphenols by identification of the characteristic structural features through structural assignments, has been addressed in this chapter.

Keywords

Antioxidant

Flavonoids

Lignans

Mass Spectrometry

NMR structural assignments

Phenolics

Polyphenols

Stilbenes

^* Department of Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 5E3, Canada; Tel: + 1 902 893 6623 [email protected]

1 Introduction and general overview

The plant derived natural products, polyphenols, were historically referred to as “vegetable tannins” as a result of the use of various plants extracts containing them in the conversion of animal skin into leather in the history of human civilization of the Ancient Greek of t...