
- 1,168 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Handbook of Toxicology of Chemical Warfare Agents
About this book
This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security.- Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market- Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time- The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book- Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with
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Information
Table of contents
- Cover Image
- Table of Contents
- Copyright
- Dedication
- List of Contributors
- Foreword
- CHAPTER 1. Introduction
- CHAPTER 2. Historical Perspective of Chemical Warfare Agents
- CHAPTER 3. Global Impact of Chemical Warfare Agents Used Before and After 1945
- CHAPTER 4. The Tokyo Subway Sarin Attack
- CHAPTER 5. Epidemiology of Chemical Warfare Agents
- CHAPTER 6. Organophosphate Nerve Agents
- CHAPTER 7. Russian VX
- CHAPTER 8. Mustards and Vesicants
- CHAPTER 9. Arsenicals
- CHAPTER 10. Psychotomimetic Agent BZ (3-Quinuclidinyl Benzilate)
- CHAPTER 11. Onchidal and Fasciculins
- CHAPTER 12. Riot Control Agents
- CHAPTER 13. Fluoroacetate
- CHAPTER 14. Strychnine
- CHAPTER 15. Superwarfarins
- CHAPTER 16. Thallium
- CHAPTER 17. Polycyclic Aromatic Hydrocarbons
- CHAPTER 18. PCBs, Dioxins, and Furans: Human Exposure and Health Effects
- CHAPTER 19. Cyanide Toxicity and its Treatment
- CHAPTER 20. Carbon Monoxide: From Public Health Risk to Painless Killer
- CHAPTER 21. Methyl Isocyanate: The Bhopal Gas
- CHAPTER 22. Chlorine
- CHAPTER 23. Phosgene
- CHAPTER 24. Other Toxic Chemicals as Potential Chemical Warfare Agents
- CHAPTER 25. Ricin and Abrin
- CHAPTER 26. Trichothecene Mycotoxins
- CHAPTER 27. Toxins of Cyanobacteria
- CHAPTER 28. Radiation and Health Effects
- CHAPTER 29. Depleted Uranium
- CHAPTER 30. Botulinum Toxin
- CHAPTER 31. Anthrax
- CHAPTER 32. The Nervous System as a Target for Chemical Warfare Agents
- CHAPTER 33. Behavioral Toxicity of Nerve Agents
- CHAPTER 34. Cardiovascular System as a Target of Chemical Warfare Agents
- CHAPTER 35. Skeletal Muscle
- CHAPTER 36. Reproductive Toxicity and Endocrine Disruption of Potential Chemical Warfare Agents
- CHAPTER 37. Liver Toxicity of Chemical Warfare Agents
- CHAPTER 38. Renal Toxicity
- CHAPTER 39. Ocular Toxicity of Sulfur Mustard
- CHAPTER 40. Immunotoxicity
- CHAPTER 41. Dermal Toxicity of Sulfur Mustard
- CHAPTER 42. Excitotoxicity, Oxidative Stress, and Neuronal Injury
- CHAPTER 43. Neuropathologic Effects of Chemical Warfare Agents
- CHAPTER 44. Molecular and Transcriptional Responses to Sarin Exposure
- CHAPTER 45. The Effects of Organophosphates in the Early Stages of Human Muscle Regeneration
- CHAPTER 46. Organophosphate Intoxication
- CHAPTER 47. Chemical Warfare Agents and Risks to Animal Health
- CHAPTER 48. Potential Agents that Can Cause Contamination of Animal Feedstuffs and Terror
- CHAPTER 49. Threats to Wildlife by Chemical Warfare Agents
- CHAPTER 50. Toxicokinetics of Chemical Warfare Agents
- CHAPTER 51. Physiologically Based Pharmacokinetic Modeling of Chemical Warfare Agents
- CHAPTER 52. Metabolism of Warfare Nerve Agents
- CHAPTER 53. On-Site Detection of Chemical Warfare Agents
- CHAPTER 54. Laboratory Analysis of Chemical Warfare Agents and Metabolites in Biomedical Samples
- CHAPTER 55. Biosensors for the Detection of OP Nerve Agents
- CHAPTER 56. Biomarkers of Exposure to Organophosphorus Poisons
- CHAPTER 57. Biomarkers and Biosensors of Delayed Neuropathic Agents
- CHAPTER 58. Monitoring of Blood Cholinesterase Activity in Workers Exposed to Nerve Agents
- CHAPTER 59. Strategies to Enhance Medical Countermeasures After the Use of Chemical Warfare Agents on Civilians
- CHAPTER 60. Medical Countermeasures and Other Therapeutic Strategies for Sulfur Mustard Toxicity
- CHAPTER 61. Medical Management of Chemical Toxicity in Pediatrics
- CHAPTER 62. Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling of Countermeasures to Nerve Agents
- CHAPTER 63. Prophylactic and Therapeutic Measures in Nerve Agent Poisoning
- CHAPTER 64. Pharmacological Prophylaxis Against Nerve Agent Poisoning: Experimental Studies and Practical Implications
- CHAPTER 65. Pyridinium Oximes as Cholinesterase Reactivators in the Treatment of OP Poisoning
- CHAPTER 66. Novel Oximes
- CHAPTER 67. Paraoxonase (PON1) and Detoxication of Nerve Agents
- CHAPTER 68. Role of Carboxylesterases in Therapeutic Intervention of Nerve Gas Poisoning
- CHAPTER 69. Protection of Acetylcholinesterase from Organophosphates
- CHAPTER 70. Catalytic Bioscavengers
- CHAPTER 71. Rapid Decontamination of Chemical Warfare Agents
- CHAPTER 72. Detoxification of Arsenic
- Index
- Plates