
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms
- 780 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms
About this book
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions.Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences.- Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress- Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention- Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress- Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment
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Information
Table of contents
- Cover image
- Title page
- Table of Contents
- Copyright
- About the author
- Preface
- Summary
- Chapter 1: Pathophysiological, toxicological, and immunoregulatory roles of reactive oxygen and nitrogen species (RONS)
- Chapter 2: Biological mechanisms of reactive oxygen species (ROS)
- Chapter 3: Cellular signaling pathways with reactive oxygen species (ROS)
- Chapter 4: Manganese as the essential element in oxidative stress and metabolic diseases
- Chapter 5: Affected energy metabolism is the primal cause of manganese toxicity
- Chapter 6: Heavy metals and free radical-induced cell death mechanisms
- Chapter 7: Cytotoxic mechanisms of xenobiotic heavy metals on oxidative stress
- Chapter 8: Oxidative stress and oxidative damage-induced cell death
- Chapter 9: Cell death mechanismsâApoptosis pathways and their implications in toxicology
- Chapter 10: Programmed cell death mechanisms and nanoparticle toxicity
- Chapter 11: Endoplasmic reticulum stress and associated ROS in disease pathophysiology applications
- Chapter 12: Endoplasmic reticulum stress-induced cell death mechanism
- Chapter 13: Modulation of endoplasmic reticulum (ER) stress of nanotoxicology for nanoparticles (NPs)
- Chapter 14: Nanoparticle cellular uptake and intracellular targeting on reactive oxygen species (ROS) in biological activities
- Chapter 15: Metal nanoparticles (MNPs) and particulate matter (PM) induce toxicity
- Chapter 16: Mechanisms for nanoparticle-mediated oxidative stress
- Chapter 17: Nanotechnological modifications of nanoparticles on reactive oxygen and nitrogen species
- Chapter 18: Medical imaging of the complexity of nanoparticles and ROS dynamics in vivo for clinical diagnosis application
- Chapter 19: Titanium dioxide nanoparticle-induced cytotoxicity and genotoxicityâGeneration of reactive oxygen species and cell damage
- Chapter 20: Toxicity of ZnO nanoparticle-induced reactive oxygen species and cancer cells
- Chapter 21: Silver nanoparticles induce cellular cytotoxicity, genotoxicity, DNA damage, and cell death
- Chapter 22: Correlations between oxidative stress and aligning nanoparticle safety assessments
- Chapter 23: Effects of interactions between antioxidant defense therapy and ROS
- Chapter 24: FDA breakthroughâDrug therapy designations for clinical evidence
- List of abbreviations
- Index